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Comparison of Dual Beam Dispersive and FTNIR Spectroscopy for Lactate Detection

1
Research Centre for Biomedical Engineering, School of Engineering and Mathematical Sciences, University of London, Northampton Square, London EC1V 0HB, UK
2
Interdisciplinary Research Centre (IRC) in Biomedical Materials, Queen Mary University of London, Mile End Road, London E1 4NS, UK
*
Author to whom correspondence should be addressed.
Academic Editor: Sayo O. Fakayode
Sensors 2021, 21(5), 1891; https://doi.org/10.3390/s21051891
Received: 7 February 2021 / Revised: 1 March 2021 / Accepted: 4 March 2021 / Published: 8 March 2021
(This article belongs to the Special Issue Optical Sensors in Health and Wellbeing)
Near Infrared (800–2500 nm) spectroscopy has been extensively used in biomedical applications, as it offers rapid, in vivo, bed-side monitoring of important haemodynamic parameters, which is especially important in critical care settings. However, the choice of NIR spectrometer needs to be investigated for biomedical applications, as both the dual beam dispersive spectrophotomer and the FTNIR spectrometer have their own advantages and disadvantages. In this study, predictive analysis of lactate concentrations in whole blood were undertaken using multivariate techniques on spectra obtained from the two spectrometer types simultaneously and results were compared. Results showed significant improvement in predicting analyte concentration when analysis was performed on full range spectral data. This is in comparison to analysis of limited spectral regions or lactate signature peaks, which yielded poorer prediction models. Furthermore, for the same region, FTNIR showed 10% better predictive capability than the dual beam dispersive NIR spectrometer. View Full-Text
Keywords: near infrared spectroscopy; dual beam dispersive NIR; FTNIR; lactate; aquaphotomics near infrared spectroscopy; dual beam dispersive NIR; FTNIR; lactate; aquaphotomics
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MDPI and ACS Style

Baishya, N.; Mamouei, M.; Budidha, K.; Qassem, M.; Vadgama, P.; Kyriacou, P.A. Comparison of Dual Beam Dispersive and FTNIR Spectroscopy for Lactate Detection. Sensors 2021, 21, 1891. https://doi.org/10.3390/s21051891

AMA Style

Baishya N, Mamouei M, Budidha K, Qassem M, Vadgama P, Kyriacou PA. Comparison of Dual Beam Dispersive and FTNIR Spectroscopy for Lactate Detection. Sensors. 2021; 21(5):1891. https://doi.org/10.3390/s21051891

Chicago/Turabian Style

Baishya, Nystha, Mohammad Mamouei, Karthik Budidha, Meha Qassem, Pankaj Vadgama, and Panayiotis A. Kyriacou 2021. "Comparison of Dual Beam Dispersive and FTNIR Spectroscopy for Lactate Detection" Sensors 21, no. 5: 1891. https://doi.org/10.3390/s21051891

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