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Article

Cloud-Based Software Architecture for Fully Automated Point-of-Care Molecular Diagnostic Device

1
School of Software, Hallym University, Chuncheon-si 24252, Korea
2
Bio-IT Research Center, Hallym University, Chuncheon-si 24252, Korea
3
Biomedux Co., Ltd., Suwon-si 16226, Korea
4
Division of Biomedical Engineering, Jeonbuk National University, Jeonju 54896, Korea
5
Research Center of Healthcare & Welfare Instrument for the Aged, Jeonbuk National University, Jeonju 54896, Korea
*
Author to whom correspondence should be addressed.
This paper is an extended version of the conference paper: Kil, B.-H.; Park, J.-S.; Park, C.-Y.; Kim, Y.-S.; Kim, J.-D. System Architecture for IIoT-Based POC Molecular Diagnostic Device. In Proceedings of the 8th Interna-tional Symposium on Sensor Science, 17–28 May 2021.
Academic Editor: Giovanna Marrazza
Sensors 2021, 21(21), 6980; https://doi.org/10.3390/s21216980
Received: 12 September 2021 / Revised: 9 October 2021 / Accepted: 19 October 2021 / Published: 21 October 2021
(This article belongs to the Special Issue I3S 2021 Selected Papers)
This paper proposes a cloud-based software architecture for fully automated point-of-care molecular diagnostic devices. The target system operates a cartridge consisting of an extraction body for DNA extraction and a PCR chip for amplification and fluorescence detection. To facilitate control and monitoring via the cloud, a socket server was employed for fundamental molecular diagnostic functions such as DNA extraction, amplification, and fluorescence detection. The user interface for experimental control and monitoring was constructed with the RESTful application programming interface, allowing access from the terminal device, edge, and cloud. Furthermore, it can also be accessed through any web-based user interface on smart computing devices such as smart phones or tablets. An emulator with the proposed software architecture was fabricated to validate successful operation. View Full-Text
Keywords: fully automated molecular diagnostic system; point-of-care; cloud-based; web-based user interface fully automated molecular diagnostic system; point-of-care; cloud-based; web-based user interface
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MDPI and ACS Style

Kil, B.-H.; Park, J.-S.; Ryu, M.-H.; Park, C.-Y.; Kim, Y.-S.; Kim, J.-D. Cloud-Based Software Architecture for Fully Automated Point-of-Care Molecular Diagnostic Device. Sensors 2021, 21, 6980. https://doi.org/10.3390/s21216980

AMA Style

Kil B-H, Park J-S, Ryu M-H, Park C-Y, Kim Y-S, Kim J-D. Cloud-Based Software Architecture for Fully Automated Point-of-Care Molecular Diagnostic Device. Sensors. 2021; 21(21):6980. https://doi.org/10.3390/s21216980

Chicago/Turabian Style

Kil, Byeong-Heon, Ji-Seong Park, Mun-Ho Ryu, Chan-Young Park, Yu-Seop Kim, and Jong-Dae Kim. 2021. "Cloud-Based Software Architecture for Fully Automated Point-of-Care Molecular Diagnostic Device" Sensors 21, no. 21: 6980. https://doi.org/10.3390/s21216980

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