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Open AccessArticle

Optical Interferometric Fringe Pattern-Incorporated Spectrum Calibration Technique for Enhanced Sensitivity of Spectral Domain Optical Coherence Tomography

1
School of Electronics Engineering, College of IT Engineering, Kyungpook National University, 80, Daehak-ro, Buk-gu, Daegu 41566, Korea
2
Department of Biomedical Engineering, College of Engineering, Kyungil University, 50, Gamasil-gil, Hayang-eup, Gyeongsan-si, Gyeongsangbuk-do 38428, Korea
3
Department of Autonomous Robot Engineering, College of Smart Engineering, Kyungil University, 50, Gamasil-gil, Hayang-eup, Gyeongsan-si, Gyeongsangbuk-do 38428, Korea
4
Department of Nuclear Energy Convergence, Kyungil University, 50, Gamasil-gil, Hayang-eup, Gyeongsan-si, Gyeongsangbuk-do 38428, Korea
5
School of Architecture and Civil Engineering, Kyungpook National University, 80, Daehak-ro, Buk-gu, Daegu 41566, Korea
*
Authors to whom correspondence should be addressed.
These authors contributed equally to this work.
Sensors 2020, 20(7), 2067; https://doi.org/10.3390/s20072067
Received: 11 February 2020 / Revised: 30 March 2020 / Accepted: 2 April 2020 / Published: 7 April 2020
(This article belongs to the Section Optical Sensors)
Depth-visualizing sensitivity can be degraded due to imperfect optical alignment and non-equidistant distribution of optical signals in the pixel array, which requires a measurement of the re-sampling process. To enhance this depth-visualizing sensitivity, reference and sample arm-channeled spectra corresponding to different depths using mirrors were obtained to calibrate the spectrum sampling prior to Fourier transformation. During the process, eight interferogram patterns corresponding to point spread function (PSF) signals at eight optical path length differences were acquired. To calibrate the spectrum, generated intensity points of the original interferogram were re-indexed towards a maximum intensity range, and these interferogram re-indexing points were employed to generate a new lookup table. The entire software-based process consists of eight consecutive steps. Experimental results revealed that the proposed method can achieve images with a high depth-visualizing sensitivity. Furthermore, the results validate the proposed method as a rapidly performable spectral calibration technique, and the real-time images acquired using our technique confirm the simplicity and applicability of the method to existing optical coherence tomography (OCT) systems. The sensitivity roll-off prior to the spectral calibration was measured as 28 dB and it was halved after the calibration process. View Full-Text
Keywords: optical coherence tomography (OCT); Point Spread Function (PSF); depth visualizing sensitivity; spectral calibration; SD-OCT optical coherence tomography (OCT); Point Spread Function (PSF); depth visualizing sensitivity; spectral calibration; SD-OCT
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MDPI and ACS Style

Han, S.; Wijesinghe, R.E.; Jeon, D.; Han, Y.; Lee, J.; Lee, J.; Jo, H.; Lee, D.-E.; Jeon, M.; Kim, J. Optical Interferometric Fringe Pattern-Incorporated Spectrum Calibration Technique for Enhanced Sensitivity of Spectral Domain Optical Coherence Tomography. Sensors 2020, 20, 2067. https://doi.org/10.3390/s20072067

AMA Style

Han S, Wijesinghe RE, Jeon D, Han Y, Lee J, Lee J, Jo H, Lee D-E, Jeon M, Kim J. Optical Interferometric Fringe Pattern-Incorporated Spectrum Calibration Technique for Enhanced Sensitivity of Spectral Domain Optical Coherence Tomography. Sensors. 2020; 20(7):2067. https://doi.org/10.3390/s20072067

Chicago/Turabian Style

Han, Sangyeob; Wijesinghe, Ruchire E.; Jeon, Deokmin; Han, Youngmin; Lee, Jaeyul; Lee, Junsoo; Jo, Hosung; Lee, Dong-Eun; Jeon, Mansik; Kim, Jeehyun. 2020. "Optical Interferometric Fringe Pattern-Incorporated Spectrum Calibration Technique for Enhanced Sensitivity of Spectral Domain Optical Coherence Tomography" Sensors 20, no. 7: 2067. https://doi.org/10.3390/s20072067

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