Next Article in Journal
Design of Quad-Port Ultra-Wideband Multiple-Input-Multiple-Output Antenna with Wide Axial-Ratio Bandwidth
Next Article in Special Issue
Electrical Resistance Sensing of Epoxy Curing Using an Embedded Carbon Nanotube Yarn
Previous Article in Journal
Calibration Procedure to Test the Effects of Multiple Influence Quantities on Low-Power Voltage Transformers
Open AccessArticle

Carbon Nanotube Yarn Microelectrodes Promote High Temporal Measurements of Serotonin Using Fast Scan Cyclic Voltammetry

Department of Chemistry and Center for Behavioral Neuroscience, American University, Washington, DC 20016, USA
*
Author to whom correspondence should be addressed.
Sensors 2020, 20(4), 1173; https://doi.org/10.3390/s20041173
Received: 31 January 2020 / Revised: 17 February 2020 / Accepted: 18 February 2020 / Published: 20 February 2020
(This article belongs to the Special Issue Carbon Nanotube Yarn-Based Sensors)
Carbon fiber-microelectrodes (CFMEs) have been the standard for neurotransmitter detection for over forty years. However, in recent years, there have been many advances of utilizing alternative nanomaterials for neurotransmitter detection with fast scan cyclic voltammetry (FSCV). Recently, carbon nanotube (CNT) yarns have been developed as the working electrode materials for neurotransmitter sensing capabilities with fast scan cyclic voltammetry. Carbon nanotubes are ideal for neurotransmitter detection because they have higher aspect ratios enabling monoamine adsorption and lower limits of detection, faster electron transfer kinetics, and a resistance to surface fouling. Several methods to modify CFMEs with CNTs have resulted in increases in sensitivity, but have also increased noise and led to irreproducible results. In this study, we utilize commercially available CNT-yarns to make microelectrodes as enhanced neurotransmitter sensors for neurotransmitters such as serotonin. CNT-yarn microelectrodes have significantly higher sensitivities (peak oxidative currents of the cyclic voltammograms) than CFMEs and faster electron transfer kinetics as measured by peak separation (ΔEP) values. Moreover, both serotonin and dopamine are adsorption controlled to the surface of the electrode as measured by scan rate and concentration experiments. CNT yarn microelectrodes also resisted surface fouling of serotonin onto the surface of the electrode over thirty minutes and had a wave application frequency independent response to sensitivity at the surface of the electrode. View Full-Text
Keywords: carbon nanotube yarn; fast scan cyclic voltammetry; serotonin; electrochemistry; carbon nanotube carbon nanotube yarn; fast scan cyclic voltammetry; serotonin; electrochemistry; carbon nanotube
Show Figures

Graphical abstract

MDPI and ACS Style

Mendoza, A.; Asrat, T.; Liu, F.; Wonnenberg, P.; Zestos, A.G. Carbon Nanotube Yarn Microelectrodes Promote High Temporal Measurements of Serotonin Using Fast Scan Cyclic Voltammetry. Sensors 2020, 20, 1173.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop