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Review

Portable and Affordable Light Source-Based Photoacoustic Tomography

1
Research and Business Development Division, CYBERDYNE INC., Stationsplein 45, A4.004, 3013 AK Rotterdam, The Netherlands
2
School of Biomedical Engineering& Imaging Sciences, King’s College London, King’s Health Partners, St Thomas’ Hospital, London SE1 7EH, UK
*
Author to whom correspondence should be addressed.
Sensors 2020, 20(21), 6173; https://doi.org/10.3390/s20216173
Received: 8 October 2020 / Revised: 27 October 2020 / Accepted: 28 October 2020 / Published: 29 October 2020
Photoacoustic imaging is a hybrid imaging modality that offers the advantages of optical (spectroscopic contrast) and ultrasound imaging (scalable spatial resolution and imaging depth). This promising modality has shown excellent potential in a wide range of preclinical and clinical imaging and sensing applications. Even though photoacoustic imaging technology has matured in research settings, its clinical translation is not happening at the expected pace. One of the main reasons for this is the requirement of bulky and expensive pulsed lasers for excitation. To accelerate the clinical translation of photoacoustic imaging and explore its potential in resource-limited settings, it is of paramount importance to develop portable and affordable light sources that can be used as the excitation light source. In this review, we focus on the following aspects: (1) the basic theory of photoacoustic imaging; (2) inexpensive light sources and different implementations; and (3) important preclinical and clinical applications, demonstrated using affordable light source-based photoacoustics. The main focus will be on laser diodes and light-emitting diodes as they have demonstrated promise in photoacoustic tomography—the key technological developments in these areas will be thoroughly reviewed. We believe that this review will be a useful opus for both the beginners and experts in the field of biomedical photoacoustic imaging. View Full-Text
Keywords: photoacoustic imaging; photoacoustic computed tomography; light-emitting diodes; laser diodes photoacoustic imaging; photoacoustic computed tomography; light-emitting diodes; laser diodes
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MDPI and ACS Style

Kuniyil Ajith Singh, M.; Xia, W. Portable and Affordable Light Source-Based Photoacoustic Tomography. Sensors 2020, 20, 6173. https://doi.org/10.3390/s20216173

AMA Style

Kuniyil Ajith Singh M, Xia W. Portable and Affordable Light Source-Based Photoacoustic Tomography. Sensors. 2020; 20(21):6173. https://doi.org/10.3390/s20216173

Chicago/Turabian Style

Kuniyil Ajith Singh, Mithun, and Wenfeng Xia. 2020. "Portable and Affordable Light Source-Based Photoacoustic Tomography" Sensors 20, no. 21: 6173. https://doi.org/10.3390/s20216173

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