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Biosensors—Recent Advances and Future Challenges in Electrode Materials
Open AccessReview

Electrochemical Biosensors Employing Natural and Artificial Heme Peroxidases on Semiconductors

Institute of Biochemistry and Biology, University of Potsdam, 14476 Potsdam, Germany
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Sensors 2020, 20(13), 3692; https://doi.org/10.3390/s20133692
Received: 4 June 2020 / Revised: 25 June 2020 / Accepted: 27 June 2020 / Published: 1 July 2020
(This article belongs to the Special Issue Biosensors – Recent Advances and Future Challenges)
Heme peroxidases are widely used as biological recognition elements in electrochemical biosensors for hydrogen peroxide and phenolic compounds. Various nature-derived and fully synthetic heme peroxidase mimics have been designed and their potential for replacing the natural enzymes in biosensors has been investigated. The use of semiconducting materials as transducers can thereby offer new opportunities with respect to catalyst immobilization, reaction stimulation, or read-out. This review focuses on approaches for the construction of electrochemical biosensors employing natural heme peroxidases as well as various mimics immobilized on semiconducting electrode surfaces. It will outline important advances made so far as well as the novel applications resulting thereof. View Full-Text
Keywords: electrochemical biosensors; heme; peroxidases; semiconductors; peroxidase mimics electrochemical biosensors; heme; peroxidases; semiconductors; peroxidase mimics
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Neumann, B.; Wollenberger, U. Electrochemical Biosensors Employing Natural and Artificial Heme Peroxidases on Semiconductors. Sensors 2020, 20, 3692.

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