Detection of the Crystallization Process of Paracetamol with a Multi-Mode Optical Fiber in a Reflective Configuration
1
INESC TEC—Institute for Systems and Computer Engineering, Technology and Science, Rua do Campo Alegre 687, 4169-007 Porto, Portugal
2
Faculty of Biotechnology of Catholic University of Portugal, Rua de Diogo Botelho, 1327, 4169-005 Porto, Portugal
3
LEPABE—Laboratory for Process Engineering, Environment, Biotechnology and Energy, Department of Chemical Engineering, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias s/n, 4200-465 Porto, Portugal
4
Department of Physics and Astronomy, Faculty of Sciences of University of Porto, Rua do Campo Alegre 687, 4169-007 Porto, Portugal
*
Author to whom correspondence should be addressed.
Sensors 2020, 20(1), 87; https://doi.org/10.3390/s20010087
Received: 14 November 2019 / Revised: 13 December 2019 / Accepted: 19 December 2019 / Published: 22 December 2019
(This article belongs to the Special Issue Optical Fiber Sensors for Biomedical Applications)
A configuration of a refractometer sensor is described with the aim of optically detecting the crystallization process of paracetamol. The developed sensing head is based on a conventional cleaved multi-mode fiber. The fiber tip sensor structure was submitted to contact with the liquid of interest (paracetamol fully dissolved in 40% v/v of ethanol/water) and the crystallization process of paracetamol, induced with continued exposure to air, was monitored in real time.
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Keywords:
paracetamol; crystallization; multi-mode optical fiber
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MDPI and ACS Style
Soares, L.; Novais, S.; Ferreira, A.; Frazão, O.; Silva, S. Detection of the Crystallization Process of Paracetamol with a Multi-Mode Optical Fiber in a Reflective Configuration. Sensors 2020, 20, 87.
AMA Style
Soares L, Novais S, Ferreira A, Frazão O, Silva S. Detection of the Crystallization Process of Paracetamol with a Multi-Mode Optical Fiber in a Reflective Configuration. Sensors. 2020; 20(1):87.
Chicago/Turabian StyleSoares, Liliana; Novais, Susana; Ferreira, António; Frazão, Orlando; Silva, Susana. 2020. "Detection of the Crystallization Process of Paracetamol with a Multi-Mode Optical Fiber in a Reflective Configuration" Sensors 20, no. 1: 87.
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