Direct Detection of Candida albicans with a Membrane Based Electrochemical Impedance Spectroscopy Sensor
AbstractCandidemia and invasive candidiasis is a cause of high mortality and morbidity rates among hospitalized patients worldwide. The occurrence of the infections increases due to the complexity of the patients and overuse of the antifungal therapy. The current Candida detection method includes blood culturing which is a lengthy procedure and thus delays the administration of the antifungal therapy. Even though the results are available after 48 h it is still the gold standard in pathogen detection in a hospital setting. In this work we present an electrochemical impedance sensor that is capable of detecting Candida albicans yeast. The yeast cells are captured on electrodes specifically functionalized with anti-Candida antibodies and detection is achieved by electrochemical impedance spectroscopy. The sensor allows for detection of the yeast cells at clinically relevant concentrations in less than 1 h. View Full-Text
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Kwasny, D.; Tehrani, S.E.; Almeida, C.; Schjødt, I.; Dimaki, M.; Svendsen, W.E. Direct Detection of Candida albicans with a Membrane Based Electrochemical Impedance Spectroscopy Sensor. Sensors 2018, 18, 2214.
Kwasny D, Tehrani SE, Almeida C, Schjødt I, Dimaki M, Svendsen WE. Direct Detection of Candida albicans with a Membrane Based Electrochemical Impedance Spectroscopy Sensor. Sensors. 2018; 18(7):2214.Chicago/Turabian Style
Kwasny, Dorota; Tehrani, Sheida E.; Almeida, Catarina; Schjødt, Ida; Dimaki, Maria; Svendsen, Winnie E. 2018. "Direct Detection of Candida albicans with a Membrane Based Electrochemical Impedance Spectroscopy Sensor." Sensors 18, no. 7: 2214.
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