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Article

A Low Cost/Low Power Open Source Sensor System for Automated Tuberculosis Drug Susceptibility Testing

1
Urban Robotics Laboratory, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Daejeon 34141, Korea
2
Department of Mechanical Engineering, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Daejeon 34141, Korea
3
School of Electrical Engineering, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Daejeon 34141, Korea
*
Author to whom correspondence should be addressed.
Academic Editors: Octavian Adrian Postolache, Alex Casson and Subhas Mukhopadhyay
Sensors 2016, 16(6), 942; https://doi.org/10.3390/s16060942
Received: 24 March 2016 / Revised: 11 June 2016 / Accepted: 16 June 2016 / Published: 22 June 2016
(This article belongs to the Special Issue Sensing Technology for Healthcare System)
In this research an open source, low power sensor node was developed to check the growth of mycobacteria in a culture bottle with a nitrate reductase assay method for a drug susceptibility test. The sensor system reports the temperature and color sensor output frequency change of the culture bottle when the device is triggered. After the culture process is finished, a nitrite ion detecting solution based on a commercial nitrite ion detection kit is injected into the culture bottle by a syringe pump to check bacterial growth by the formation of a pigment by the reaction between the solution and the color sensor. Sensor status and NRA results are broadcasted via a Bluetooth low energy beacon. An Android application was developed to collect the broadcasted data, classify the status of cultured samples from multiple devices, and visualize the data for the end users, circumventing the need to examine each culture bottle manually during a long culture period. The authors expect that usage of the developed sensor will decrease the cost and required labor for handling large amounts of patient samples in local health centers in developing countries. All 3D-printerable hardware parts, a circuit diagram, and software are available online. View Full-Text
Keywords: mycobacteria; nitrate reductase assay; drug susceptibility test; sensor node; Bluetooth low energy beacon; 3D-printer; low power; low cost mycobacteria; nitrate reductase assay; drug susceptibility test; sensor node; Bluetooth low energy beacon; 3D-printer; low power; low cost
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MDPI and ACS Style

Kim, K.; Kim, H.K.; Lim, H.; Myung, H. A Low Cost/Low Power Open Source Sensor System for Automated Tuberculosis Drug Susceptibility Testing. Sensors 2016, 16, 942. https://doi.org/10.3390/s16060942

AMA Style

Kim K, Kim HK, Lim H, Myung H. A Low Cost/Low Power Open Source Sensor System for Automated Tuberculosis Drug Susceptibility Testing. Sensors. 2016; 16(6):942. https://doi.org/10.3390/s16060942

Chicago/Turabian Style

Kim, Kyukwang, Hyeong Keun Kim, Hwijoon Lim, and Hyun Myung. 2016. "A Low Cost/Low Power Open Source Sensor System for Automated Tuberculosis Drug Susceptibility Testing" Sensors 16, no. 6: 942. https://doi.org/10.3390/s16060942

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