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Open AccessCommunication

Synthesis of Polar Aromatic Substituted Terminal Alkynes from Propargyl Amine

1
Department of Chemistry, Wake Forest University, Winston-Salem, NC 27101, USA
2
Center for Functional Materials, Department of Chemistry, Wake Forest University, Winston-Salem, NC 27101, USA
*
Author to whom correspondence should be addressed.
Academic Editors: Dimitrios Matiadis, Rodrigo Abonia and Eleftherios Halevas
Molbank 2021, 2021(2), M1206; https://doi.org/10.3390/M1206
Received: 20 March 2021 / Revised: 6 April 2021 / Accepted: 19 April 2021 / Published: 25 April 2021
A series of small molecules containing polar aromatic substituents and alkynes have been synthesized. One–pot preparations of polar aromatic molecules containing an alkynyl imine and alkynyl amide are reported. A one-pot preparation of a catechol containing an alkynyl amine was also attempted but in our hands it proved much better to synthesize this target molecule via a three step synthesis which we also report here. View Full-Text
Keywords: catechol; alkyne; thiol-alkyne click reaction catechol; alkyne; thiol-alkyne click reaction
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MDPI and ACS Style

Banks, S.R.; Yoo, K.M.; Welker, M.E. Synthesis of Polar Aromatic Substituted Terminal Alkynes from Propargyl Amine. Molbank 2021, 2021, M1206. https://doi.org/10.3390/M1206

AMA Style

Banks SR, Yoo KM, Welker ME. Synthesis of Polar Aromatic Substituted Terminal Alkynes from Propargyl Amine. Molbank. 2021; 2021(2):M1206. https://doi.org/10.3390/M1206

Chicago/Turabian Style

Banks, Surya R.; Yoo, Kyung M.; Welker, Mark E. 2021. "Synthesis of Polar Aromatic Substituted Terminal Alkynes from Propargyl Amine" Molbank 2021, no. 2: M1206. https://doi.org/10.3390/M1206

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