Planar-Chiral P and N-bridged Diferrocenes
Institute of Computational Biological Chemistry, University of Vienna, Währinger Straße 17, 1090 Vienna, Austria
Institute of Organic Chemistry, University of Vienna, Währinger Straße 38, 1090 Vienna, Austria
Institute of Chemical Catalysis, University of Vienna, Währinger Straße 38, 1090 Vienna, Austria
Author to whom correspondence should be addressed.
Molbank 2020, 2020(2), M1130; https://doi.org/10.3390/M1130
Received: 1 April 2020 / Revised: 25 April 2020 / Accepted: 29 April 2020 / Published: 4 May 2020
(This article belongs to the Section Organic Synthesis)
We describe the synthesis of planar-chiral diferrocene compounds 4, 7 and 12, intended as key precursors for a new family of asymmetric catalyst ligands with less complex structures than their popular equivalents. In contrast to conventional 1,2-disubstituted ferrocenes containing center-chiral and planar-chiral elements, these compounds are purely planar-chiral due to the absence of α-substiuted ethyl groups. The title compounds 4, 7 and 12 were obtained from known precursors in 87%, 59% and 60% yields, respectively.