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6-Imino-1,2,3,4,8,9,10,11-octahydropyrido[1,2-a]pyrido[1′,2′:1,2]imidazo[4,5-f]benzimidazole-13-one: Synthesis and Cytotoxicity Evaluation

Department of Pharmacy, School of Life Sciences, Pharmacy and Chemistry, Kingston University, Penrhyn Road, Kingston upon Thames KT1 2EE, UK
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Molbank 2020, 2020(1), M1118; https://doi.org/10.3390/M1118
Received: 23 February 2020 / Revised: 3 March 2020 / Accepted: 4 March 2020 / Published: 5 March 2020
(This article belongs to the Special Issue Heterocycle Reactions)
The first report of an iminoquinone of imidazo[4,5-f]benzimidazole is described. The 2D-NOESY spectrum of 1,2,3,4,8,9,10,11-octahydropyrido[1,2-a]pyrido[1’,2’:1,2]imidazo[4,5-f]benzimidazol-6-amine was used to confirm the location of the imine moiety at the C-6 position of the title compound. Cytotoxicity data from the National Cancer Institute are included. View Full-Text
Keywords: imidazobenzimidazoles; Frémy oxidation; nitrogen heterocycles; quinone imidazobenzimidazoles; Frémy oxidation; nitrogen heterocycles; quinone
MDPI and ACS Style

Conboy, D.; Aldabbagh, F. 6-Imino-1,2,3,4,8,9,10,11-octahydropyrido[1,2-a]pyrido[1′,2′:1,2]imidazo[4,5-f]benzimidazole-13-one: Synthesis and Cytotoxicity Evaluation. Molbank 2020, 2020, M1118.

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