Next Article in Journal
Paenidigyamycin G: 1-Acetyl-2,4-dimethyl-3-phenethyl-1H-imidazol-3-ium
Next Article in Special Issue
(E)-(1-(4-Ethoxycarbonylphenyl)-5-(3,4-dimethoxyphenyl)-3-(3,4-dimethoxystyryl)-2-pyrazoline: Synthesis, Characterization, DNA-Interaction, and Evaluation of Activity Against Drug-Resistant Cell Lines
Previous Article in Journal
1,1,4,7-Tetramethyldecahydro-1H-cyclopropa[e]azulen-7-ol from the Stembark Chisocheton pentandrus
Previous Article in Special Issue
Synthesis of 2-Cyanopyrimidines
 
Search for Articles:
Title / Keyword
Author / Affiliation
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
Journals
Molbank
Volume 2019
Issue 4
10.3390/M1093
molbank-logo
Submit to this Journal Review for this Journal Edit a Special Issue
► Article Menu

Article Menu

share announcement thumb_up
...
textsms
...
Open AccessShort Note

2,2′-((1,4-Dimethoxy-1,4-dioxobutane-2,3-diylidene)bis(azanylylidene))bis(quinoline-3-carboxylic acid)

by
Joanna Fedorowicz
1,*,
Karol Gzella
1,
Paulina Wiśniewska
2 and
Jarosław Sączewski
2
1
Department of Chemical Technology of Drugs, Faculty of Pharmacy, Medical University of Gdańsk, Al. Gen. J. Hallera 107, Gdańsk 80-416, Poland
2
Department of Organic Chemistry, Faculty of Pharmacy, Medical University of Gdańsk, Al. Gen. J. Hallera 107, Gdańsk 80-416, Poland
*
Author to whom correspondence should be addressed.
Molbank 2019, 2019(4), M1093; https://doi.org/10.3390/M1093
Received: 27 October 2019 / Revised: 19 November 2019 / Accepted: 19 November 2019 / Published: 21 November 2019
(This article belongs to the Special Issue Nitrogen-Containing Molecules: Natural and Synthetic Products Including Coordination Compounds)
View Full-Text Download PDF
Browse Figure

Abstract

The title compound, 2,2′-((1,4-dimethoxy-1,4-dioxobutane-2,3-diylidene)bis(azanylylidene))bis(quinoline-3-carboxylic acid) was synthesized from isoxazolo[3,4-b]quinolin-3(1H)-one and dimethyl acetylenedicarboxylate (DMAD) via a double aza-Michael addition followed by [1,3]-H shifts. The product was characterized by infrared and nuclear magnetic resonance spectroscopy, as well as elemental analysis and high-resolution mass spectrometry (HRMS). The proposed reaction mechanism was rationalized by density functional theory (DFT) calculations. View Full-Text
Keywords: [1,3]-H shift; aza-Michael addition; DFT calculations; dimethyl acetylenedicarboxylate; isoxazolo[3,4-b]quinolin-3(1H)-one [1,3]-H shift; aza-Michael addition; DFT calculations; dimethyl acetylenedicarboxylate; isoxazolo[3,4-b]quinolin-3(1H)-one
►▼ Show Figures

Graphical abstract

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

Supplementary Materials

SciFeed

Share and Cite

MDPI and ACS Style

Fedorowicz, J.; Gzella, K.; Wiśniewska, P.; Sączewski, J. 2,2′-((1,4-Dimethoxy-1,4-dioxobutane-2,3-diylidene)bis(azanylylidene))bis(quinoline-3-carboxylic acid). Molbank 2019, 2019, M1093. https://doi.org/10.3390/M1093

AMA Style

Fedorowicz J, Gzella K, Wiśniewska P, Sączewski J. 2,2′-((1,4-Dimethoxy-1,4-dioxobutane-2,3-diylidene)bis(azanylylidene))bis(quinoline-3-carboxylic acid). Molbank. 2019; 2019(4):M1093. https://doi.org/10.3390/M1093

Chicago/Turabian Style

Fedorowicz, Joanna; Gzella, Karol; Wiśniewska, Paulina; Sączewski, Jarosław. 2019. "2,2′-((1,4-Dimethoxy-1,4-dioxobutane-2,3-diylidene)bis(azanylylidene))bis(quinoline-3-carboxylic acid)" Molbank 2019, no. 4: M1093. https://doi.org/10.3390/M1093

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Metrics

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop