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N-Benzo[c][1,2,5]thiazol-4-yl-3-trifluoromethylbenzamide

Department of Chemistry, College of Science, Sultan Qaboos University, PO Box 36, Al Khoudh, Muscat 123, Oman
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Molbank 2019, 2019(3), M1075; https://doi.org/10.3390/M1075
Received: 2 July 2019 / Revised: 18 July 2019 / Accepted: 24 July 2019 / Published: 29 July 2019
(This article belongs to the Section Organic Synthesis)
The title compound, N-benzo[c][1,2,5]thiazol-4-yl-3-trifluoromethylbenzamide (1) was synthesized by reacting 3-trifluoromethylbenzoyl chloride (4) and 4-aminobenzo[c][1,2,5]thiadiazole (5). The compound was characterized by various spectroscopic methods (1H NMR, 13C NMR, IR, GC-MS) and its composition confirmed by elemental analysis. The importance of this compound lies in its possession of an N,N-bidentate directing group. Such a structural motif is potentially suitable for metal-catalyzed C-H bond functionalization reactions. View Full-Text
Keywords: benzamide; bidentate directing group; C-H functionalization benzamide; bidentate directing group; C-H functionalization
MDPI and ACS Style

Al Mamari, H.H.; Al Awaimri, N.; Al Lawati, Y. N-Benzo[c][1,2,5]thiazol-4-yl-3-trifluoromethylbenzamide. Molbank 2019, 2019, M1075.

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