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Department of Chemistry, College of Science, Sultan Qaboos University, PO Box 36, Al Khoudh, Muscat 123, Oman
Author to whom correspondence should be addressed.
Molbank 2019, 2019(3), M1075;
Received: 2 July 2019 / Revised: 18 July 2019 / Accepted: 24 July 2019 / Published: 29 July 2019
(This article belongs to the Section Organic Synthesis)
PDF [929 KB, uploaded 29 July 2019]


The title compound, N-benzo[c][1,2,5]thiazol-4-yl-3-trifluoromethylbenzamide (1) was synthesized by reacting 3-trifluoromethylbenzoyl chloride (4) and 4-aminobenzo[c][1,2,5]thiadiazole (5). The compound was characterized by various spectroscopic methods (1H NMR, 13C NMR, IR, GC-MS) and its composition confirmed by elemental analysis. The importance of this compound lies in its possession of an N,N-bidentate directing group. Such a structural motif is potentially suitable for metal-catalyzed C-H bond functionalization reactions. View Full-Text
Keywords: benzamide; bidentate directing group; C-H functionalization benzamide; bidentate directing group; C-H functionalization
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Al Mamari, H.H.; Al Awaimri, N.; Al Lawati, Y. N-Benzo[c][1,2,5]thiazol-4-yl-3-trifluoromethylbenzamide. Molbank 2019, 2019, M1075.

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