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Open AccessCommunication

1-Methyl-3-{4-[(4-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidin-1-yl)benzyl]}-2-phenylindole

1
Laboratoire ARNA, INSERM U1212 / UMR CNRS 5320, UFR des Sciences Pharmaceutiques, Univ. Bordeaux, 146 rue Léo Saignat, CEDEX, F-33076 Bordeaux, France
2
Cellules souches hématopoïétiques normales et leucémiques, INSERM U1035, UFR des Sciences Pharmaceutiques, Univ. Bordeaux, CEDEX, F-33076 Bordeaux, France
*
Author to whom correspondence should be addressed.
Molbank 2018, 2018(4), M1023; https://doi.org/10.3390/M1023
Received: 25 September 2018 / Revised: 1 October 2018 / Accepted: 2 October 2018 / Published: 4 October 2018
(This article belongs to the Section Organic Synthesis)
The 1-methyl-3-{4-[(4-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidin-1-yl)benzyl]}-2-phenylindole compound has been successfully synthesized via a multistep pathway starting from 2-phenylindole. Structure characterization of this new indole derivative was done by FTIR, 1H-NMR, 13C-NMR, and HRMS spectral analysis. The title compound showed high cytotoxic potential against five leukemia cell lines (K562, HL60, U937, U266, and Jurkat cell lines). View Full-Text
Keywords: indole derivative; leukemia; antiproliferative activity indole derivative; leukemia; antiproliferative activity
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MDPI and ACS Style

Guillon, J.; Savrimoutou, S.; Rubio, S.; Desplat, V. 1-Methyl-3-{4-[(4-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidin-1-yl)benzyl]}-2-phenylindole. Molbank 2018, 2018, M1023. https://doi.org/10.3390/M1023

AMA Style

Guillon J, Savrimoutou S, Rubio S, Desplat V. 1-Methyl-3-{4-[(4-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidin-1-yl)benzyl]}-2-phenylindole. Molbank. 2018; 2018(4):M1023. https://doi.org/10.3390/M1023

Chicago/Turabian Style

Guillon, Jean; Savrimoutou, Solène; Rubio, Sandra; Desplat, Vanessa. 2018. "1-Methyl-3-{4-[(4-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidin-1-yl)benzyl]}-2-phenylindole" Molbank 2018, no. 4: M1023. https://doi.org/10.3390/M1023

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