Next Article in Journal
Previous Article in Journal
Article Menu

Export Article

Open AccessShort Note


Department of Pharmacy, Sekolah Tinggi Ilmu Kesehatan Bakti Tunas Husada, Jl. Cilolohan No. 36, Tasikmalaya 46115, Indonesia
Scientific Consortium for Drug Discovery and Development, Faculty of Pharmacy, Universitas Padjadjaran, Bandung 45363, Indonesia
Department of Pharmacy, Universitas Perjuangan, Jl. Pembela Tanah Air 177, Tasikmalaya 46115, Indonesia
Faculty of Pharmacy, Airlangga University, Jl. Darmawangsa Dalam 4-6, Surabaya 60286, Indonesia
Author to whom correspondence should be addressed.
Molbank 2018, 2018(3), M1005;
Received: 12 June 2018 / Revised: 5 July 2018 / Accepted: 6 July 2018 / Published: 9 July 2018
(This article belongs to the Section Organic Synthesis)
PDF [360 KB, uploaded 9 July 2018]


The 1-(4-hexylbenzoyl)-3-methylthiourea compound has been successfully synthesized by reacting 4-hexylbenzoyl chloride and 1-methylthiourea via the reflux method using a triethylamine catalyst. The 1-(4-hexylbenzoyl)-3-methylthiourea compound was identified by UV-visible, FT-IR, 13C/1H-NMR and Mass spectrophotometry. From the activity test on four cancer cell lines (HeLa, T47D, WiDr and MCF7 cell), it could be seen that it had better activity on four cancer cells than the control, hydroxyurea. View Full-Text
Keywords: acylation reaction; cancer; spectrophotometry; thiourea acylation reaction; cancer; spectrophotometry; thiourea
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

Supplementary materials


Share & Cite This Article

MDPI and ACS Style

Ruswanto, R.; Mardianingrum, R.; Lestari, T.; Nofianti, T.; Siswandono, S. 1-(4-Hexylbenzoyl)-3-methylthiourea. Molbank 2018, 2018, M1005.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Molbank EISSN 1422-8599 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top