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Acknowledgement to Reviewers of Molbank in 2016
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Molbank 2017, 2017(1), M927;


Department of Chemistry, University of Parma, Parco Area delle Scienze 17/A, 43124 Parma, Italy
Laboratory of Industrial and Synthetic Organic Chemistry (LISOC), Department of Chemistry and Chemical Technologies, University of Calabria, Via Pietro Bucci 12/C, 87036 Arcavacata di Rende (CS), Italy
Author to whom correspondence should be addressed.
Academic Editor: Norbert Haider
Received: 20 December 2016 / Revised: 5 January 2017 / Accepted: 9 January 2017 / Published: 13 January 2017
(This article belongs to the Section Organic Synthesis)
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The title compound, (Z)-4-(carbomethoxymethylene)-2-(4-fluorophenyl)-4H-benzo[d][1,3]oxazine, was synthesized in 68% isolated yield by palladium-catalyzed oxidative cyclization-methoxycarbonylation of 4-fluoro-N-(2-((trimethylsilyl)ethynyl)phenyl)benzamide. This new heterocyclic derivative was fully characterized by IR, 1H-NMR, 13C-NMR spectroscopies, MS spectrometry, and elemental analysis. The Z configuration around the double bond was unequivocally established by 2D NOESY experiments. View Full-Text
Keywords: palladium; benzoxazines; carbonylation; Heterocyclization; 2D NMR experiments palladium; benzoxazines; carbonylation; Heterocyclization; 2D NMR experiments
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Pancrazzi, F.; Motti, E.; Costa, M.; Mancuso, R.; Gabriele, B.; Della Ca’, N. (Z)-4-(Carbomethoxymethylene)-2-(4-fluorophenyl)-4H-benzo[d][1,3]oxazine. Molbank 2017, 2017, M927.

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