Chitooligosaccharide-2,5-anhydro-D-mannonic Acid
Abstract
Chitooligosaccharide with one 2,5-anhydro-D-mannofuranose unit at the reducing end (COSamf) was prepared by nitrous deamination of fully N-deacetylated chitosan. The oxidation of the amf-unit by chlorite sodium was achieved in high yield. The chemical structure of the targeted chitooligosaccharide-2,5-anhydro-D-mannonic acid with a degree of polymerization ~10 was fully characterized by NMR spectroscopy, MALDI-TOF mass spectrometry and size-exclusion chromatography. The success of this synthesis opens the way to a new generation of end-functionalized COS building blocks. View Full-TextSupplementary materials
- Supplementary File 1:
3D structure (MOL, 3 KB)
Display in MOL Viewer
3D structure generated by CORINA by Molecular Networks. - Supplementary File 2:
INCHI-Document (INCHI, 823 B)
- Supplementary File 3:
MOL-Document (MOL, 3 KB)
Display in MOL Viewer
- Supplementary File 4:
Supporting Information (PDF, 2033 KB)
Share & Cite This Article
Salim, E.; Ailincai, D.; Trombotto, S. Chitooligosaccharide-2,5-anhydro-D-mannonic Acid. Molbank 2014, 2014, M832.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.