Dietary Flavonoids Sensitize HeLa Cells to Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL)
Abstract
:1. Introduction
2. Results and Discussion
3. Conclusions
4. Experimental Section
4.1. General
4.2. Cell culture
4.3. Cytotoxicity assay
MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay
4.4. LDH (lactate dehydrogenase) release assay
4.5. Detection of apoptosis
4.6. Statistical analysis
References
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Compound | IC50 (μM)a | |
---|---|---|
1 | Flavone | 49.69±1.08 |
2 | Apigenin | 43.05±0.86 |
3 | Kaempferol | ndb |
4 | Quercetin | nd |
5 | Genistein | 49.64±2.43 |
Share and Cite
Szliszka, E.; Czuba, Z.P.; Jernas, K.; Król, W. Dietary Flavonoids Sensitize HeLa Cells to Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL). Int. J. Mol. Sci. 2008, 9, 56-64. https://doi.org/10.3390/ijms9010056
Szliszka E, Czuba ZP, Jernas K, Król W. Dietary Flavonoids Sensitize HeLa Cells to Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL). International Journal of Molecular Sciences. 2008; 9(1):56-64. https://doi.org/10.3390/ijms9010056
Chicago/Turabian StyleSzliszka, Ewelina, Zenon P. Czuba, Katarzyna Jernas, and Wojciech Król. 2008. "Dietary Flavonoids Sensitize HeLa Cells to Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL)" International Journal of Molecular Sciences 9, no. 1: 56-64. https://doi.org/10.3390/ijms9010056