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Correction to Int. J. Mol. Sci. 2022, 23(8), 4169.
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Correction

Correction: Smolarz et al. Radiation-Induced Bystander Effect Mediated by Exosomes Involves the Replication Stress in Recipient Cells. Int. J. Mol. Sci. 2022, 23, 4169

by
Mateusz Smolarz
1,
Łukasz Skoczylas
1,
Marta Gawin
1,
Monika Krzyżowska
1,
Monika Pietrowska
1 and
Piotr Widłak
2,*
1
Maria Skłodowska-Curie National Research Institute of Oncology, 44-102 Gliwice, Poland
2
2nd Department of Radiology, Medical University of Gdańsk, 80-210 Gdańsk, Poland
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2026, 27(7), 3254; https://doi.org/10.3390/ijms27073254
Submission received: 27 March 2026 / Accepted: 30 March 2026 / Published: 3 April 2026
(This article belongs to the Special Issue Effects of Ionizing Radiation in Cancer Radiotherapy)
Browse Figure
Versions Notes
In the original publication [1], there was a mistake in Figure 2 as published. In panel A of Figure 2, the small representative inset intended to illustrate the response of cells incubated with exosomes released by irradiated cells (Ex_2Gy) was mistakenly taken from an incorrect subfolder containing insets of irradiated cells. Following correction, the appropriate representative inset derived from the correct micrograph illustrating cells incubated with exosomes released by irradiated cells was used to prepare the revised version of Figure 2A. The corrected Figure 2 and caption appear below. The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.

Reference

  1. Smolarz, M.; Skoczylas, Ł.; Gawin, M.; Krzyżowska, M.; Pietrowska, M.; Widłak, P. Radiation-Induced Bystander Effect Mediated by Exosomes Involves the Replication Stress in Recipient Cells. Int. J. Mol. Sci. 2022, 23, 4169. [Google Scholar] [CrossRef] [PubMed]
Ijms 27 03254 g002
Figure 2. Induction of γH2A.X foci by exosomes from irradiated cells. (A) Visualization of γH2A.X foci in FaDu cells co-incubated (1 h) with exosomes released by sham-irradiated (Ex_0Gy) or irradiated (Ex_2Gy) cells; untreated cells (PBS control, Ctr) or cells directly irradiated with 2Gy (IR) were used as controls. (B) The number γH2A.X foci after different times of co-incubation with exosomes (1–23 h). (C) The number γH2A.X foci after 1 and 3 h of co-incubation with exosomes; directly irradiated cells (IR) were analyzed 1 h after irradiation. (D) The relative intensity of γH2A.X foci after 1 h of co-incubation; the amounts of Ex_0Gy and Ex_2Gy exosomes were normalized according to the number of donor cells (Cell norm.) or according to the Total Exosome Proteins (TEP norm.); the nucleus-integrated intensity was expressed as a fold-change versus PBS-treated controls (FC vs. Ctr). Box plots show the median, minimum, maximum, lower, and upper quartile; statistically significant differences between groups are represented by asterisks: (*) = p < 0.05, (**) = p < 0.001 (only differences between Ctr and exosome-stimulated cells are shown for clarity).
Figure 2. Induction of γH2A.X foci by exosomes from irradiated cells. (A) Visualization of γH2A.X foci in FaDu cells co-incubated (1 h) with exosomes released by sham-irradiated (Ex_0Gy) or irradiated (Ex_2Gy) cells; untreated cells (PBS control, Ctr) or cells directly irradiated with 2Gy (IR) were used as controls. (B) The number γH2A.X foci after different times of co-incubation with exosomes (1–23 h). (C) The number γH2A.X foci after 1 and 3 h of co-incubation with exosomes; directly irradiated cells (IR) were analyzed 1 h after irradiation. (D) The relative intensity of γH2A.X foci after 1 h of co-incubation; the amounts of Ex_0Gy and Ex_2Gy exosomes were normalized according to the number of donor cells (Cell norm.) or according to the Total Exosome Proteins (TEP norm.); the nucleus-integrated intensity was expressed as a fold-change versus PBS-treated controls (FC vs. Ctr). Box plots show the median, minimum, maximum, lower, and upper quartile; statistically significant differences between groups are represented by asterisks: (*) = p < 0.05, (**) = p < 0.001 (only differences between Ctr and exosome-stimulated cells are shown for clarity).
Ijms 27 03254 g002
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MDPI and ACS Style

Smolarz, M.; Skoczylas, Ł.; Gawin, M.; Krzyżowska, M.; Pietrowska, M.; Widłak, P. Correction: Smolarz et al. Radiation-Induced Bystander Effect Mediated by Exosomes Involves the Replication Stress in Recipient Cells. Int. J. Mol. Sci. 2022, 23, 4169. Int. J. Mol. Sci. 2026, 27, 3254. https://doi.org/10.3390/ijms27073254

AMA Style

Smolarz M, Skoczylas Ł, Gawin M, Krzyżowska M, Pietrowska M, Widłak P. Correction: Smolarz et al. Radiation-Induced Bystander Effect Mediated by Exosomes Involves the Replication Stress in Recipient Cells. Int. J. Mol. Sci. 2022, 23, 4169. International Journal of Molecular Sciences. 2026; 27(7):3254. https://doi.org/10.3390/ijms27073254

Chicago/Turabian Style

Smolarz, Mateusz, Łukasz Skoczylas, Marta Gawin, Monika Krzyżowska, Monika Pietrowska, and Piotr Widłak. 2026. "Correction: Smolarz et al. Radiation-Induced Bystander Effect Mediated by Exosomes Involves the Replication Stress in Recipient Cells. Int. J. Mol. Sci. 2022, 23, 4169" International Journal of Molecular Sciences 27, no. 7: 3254. https://doi.org/10.3390/ijms27073254

APA Style

Smolarz, M., Skoczylas, Ł., Gawin, M., Krzyżowska, M., Pietrowska, M., & Widłak, P. (2026). Correction: Smolarz et al. Radiation-Induced Bystander Effect Mediated by Exosomes Involves the Replication Stress in Recipient Cells. Int. J. Mol. Sci. 2022, 23, 4169. International Journal of Molecular Sciences, 27(7), 3254. https://doi.org/10.3390/ijms27073254

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