Radiation-Induced Synchronous Parathyroid Carcinoma and Papillary Thyroid Carcinoma: Clinical, Morphological, and Genetic Insights
Abstract
1. Introduction
2. Case Presentation
2.1. Medical History, Clinical Findings
2.2. Investigations of the Thyroid and Parathyroid Gland
2.3. Pathological Investigations
2.4. Genomic Profiling of Parathyroid Carcinoma and Papillary Thyroid Carcinoma
2.5. Postoperative Treatment and Follow-Up
3. Discussion
4. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Measured Value | Normal Value Range | |
---|---|---|
Sodium (mmol/L) | 136 | 136–145 |
Potassium (mmol/L) | 4.8 | 3.5–5.1 |
Calcium (mmol/L) | 3.48 | 2.20–2.55 |
Albumin-adjusted calcium (mmol/L) | 3.46 | 2.20–2.55 |
Magnesium (mmol/L) | 0.73 | 0.7–1.05 |
Phosphorus (mmol/L) | 0.51 | 0.87–1.45 |
Alkaline phosphatase (U/L) | 463 | 35–104 |
Carbamide (mmol/L) | 6.4 | 2.1–7.1 |
Creatinine (µmol/L) | 96 | 53–97 |
eGFR-EPI (ml/min/1.73 m2) | 77 | 90< |
Parathormone (pmol/L) | 150 | 1.6–6.9 |
Urinary calcium excretion (mmol/L) | 423 | 1.25–3.75 |
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Iványi, G.; Christofi, A.; Sipka, G.; Zombori, T.; Kuthi, L.; Simon, A.; Dobi, D.; Lázár, G.; Valkusz, Z.; Iványi, B. Radiation-Induced Synchronous Parathyroid Carcinoma and Papillary Thyroid Carcinoma: Clinical, Morphological, and Genetic Insights. Int. J. Mol. Sci. 2025, 26, 4441. https://doi.org/10.3390/ijms26094441
Iványi G, Christofi A, Sipka G, Zombori T, Kuthi L, Simon A, Dobi D, Lázár G, Valkusz Z, Iványi B. Radiation-Induced Synchronous Parathyroid Carcinoma and Papillary Thyroid Carcinoma: Clinical, Morphological, and Genetic Insights. International Journal of Molecular Sciences. 2025; 26(9):4441. https://doi.org/10.3390/ijms26094441
Chicago/Turabian StyleIványi, Gábor, Alexandros Christofi, Gábor Sipka, Tamás Zombori, Levente Kuthi, Andrea Simon, Deján Dobi, György Lázár, Zsuzsanna Valkusz, and Béla Iványi. 2025. "Radiation-Induced Synchronous Parathyroid Carcinoma and Papillary Thyroid Carcinoma: Clinical, Morphological, and Genetic Insights" International Journal of Molecular Sciences 26, no. 9: 4441. https://doi.org/10.3390/ijms26094441
APA StyleIványi, G., Christofi, A., Sipka, G., Zombori, T., Kuthi, L., Simon, A., Dobi, D., Lázár, G., Valkusz, Z., & Iványi, B. (2025). Radiation-Induced Synchronous Parathyroid Carcinoma and Papillary Thyroid Carcinoma: Clinical, Morphological, and Genetic Insights. International Journal of Molecular Sciences, 26(9), 4441. https://doi.org/10.3390/ijms26094441