Next Article in Journal
The Effect of Parental Faecal Microbiome Transplantation from Children with Autism Spectrum Disorder on Behavior and Gastrointestinal Manifestations in the Male Offspring of Shank3 Mice
Previous Article in Journal
Metformin Degradation by Advanced Oxidation Processes: Performance, Limitations, and Environmental Concerns
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
IJMS
Volume 26
Issue 13
10.3390/ijms26135922
ijms-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
Retraction of Int. J. Mol. Sci. 2015, 16(10), 23823-23848.
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Retraction

RETRACTED: Zhang et al. Shikonin Inhibits the Migration and Invasion of Human Glioblastoma Cells by Targeting Phosphorylated β-Catenin and Phosphorylated PI3K/Akt: A Potential Mechanism for the Anti-Glioma Efficacy of a Traditional Chinese Herbal Medicine. Int. J. Mol. Sci. 2015, 16, 23823–23848

by
Feng-Ying Zhang
1,2,
Yi Hu
3,
Zhong-You Que
3,
Ping Wang
1,2,
Yun-Hui Liu
3,
Zhen-Hua Wang
4 and
Yi-Xue Xue
1,2,*
1
Department of Neurobiology, College of Basic Medicine, China Medical University, Shenyang 110122, China
2
Institute of Pathology and Pathophysiology, China Medical University, Shenyang 110122, China
3
Department of Neurosurgery, Shengjing Hospital of China Medical University, Shenyang 110004, China
4
Department of Physiology, College of Basic Medicine, China Medical University, Shenyang 110122, China
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2025, 26(13), 5922; https://doi.org/10.3390/ijms26135922
Submission received: 4 June 2025 / Accepted: 10 June 2025 / Published: 20 June 2025
(This article belongs to the Section Bioactives and Nutraceuticals)
Versions Notes
The journal retracts the article titled “Shikonin Inhibits the Migration and Invasion of Human Glioblastoma Cells by Targeting Phosphorylated β-Catenin and Phosphorylated PI3K/Akt: A Potential Mechanism for the Anti-Glioma Efficacy of a Traditional Chinese Herbal Medicine” [1], cited above.
Following publication, concerns were brought to the attention of the Editorial Office regarding the integrity of a number of images presented in this article [1].
Adhering to our standard procedure, the Editorial Office and Editorial Board conducted an investigation that confirmed image modification and duplication between Figure 2A,B published in [1], within Figure 8 in [1], and between Figures 2 and 3 in [1] and Figures 2C and 5B in [2], presenting different experimental conditions. The authors were contacted on multiple occasions but failed to respond. Consequently, the Editorial Board has lost confidence in the reliability of the findings and decided to retract this publication [1] as per MDPI’s retraction policy (https://www.mdpi.com/ethics#_bookmark30).
This retraction was approved by the Editor-in-Chief of the International Journal of Molecular Science.
The authors did not provide a comment on this decision.

References

  1. Zhang, F.-Y.; Hu, Y.; Que, Z.-Y.; Wang, P.; Liu, Y.-H.; Wang, Z.-H.; Xue, Y.-X. RETRACTED: Shikonin Inhibits the Migration and Invasion of Human Glioblastoma Cells by Targeting Phosphorylated β-Catenin and Phosphorylated PI3K/Akt: A Potential Mechanism for the Anti-Glioma Efficacy of a Traditional Chinese Herbal Medicine. Int. J. Mol. Sci. 2015, 16, 23823–23848. [Google Scholar] [CrossRef] [PubMed]
  2. Wang, P.; Liu, Y.H.; Yao, Y.L.; Li, Z.; Li, Z.Q.; Ma, J.; Xue, Y.X. Long non-coding RNA CASC2 suppresses malignancy in human gliomas by miR-21. Cell Signal. 2015, 27, 275–282. [Google Scholar] [CrossRef] [PubMed]
Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content.

Share and Cite

MDPI and ACS Style

Zhang, F.-Y.; Hu, Y.; Que, Z.-Y.; Wang, P.; Liu, Y.-H.; Wang, Z.-H.; Xue, Y.-X. RETRACTED: Zhang et al. Shikonin Inhibits the Migration and Invasion of Human Glioblastoma Cells by Targeting Phosphorylated β-Catenin and Phosphorylated PI3K/Akt: A Potential Mechanism for the Anti-Glioma Efficacy of a Traditional Chinese Herbal Medicine. Int. J. Mol. Sci. 2015, 16, 23823–23848. Int. J. Mol. Sci. 2025, 26, 5922. https://doi.org/10.3390/ijms26135922

AMA Style

Zhang F-Y, Hu Y, Que Z-Y, Wang P, Liu Y-H, Wang Z-H, Xue Y-X. RETRACTED: Zhang et al. Shikonin Inhibits the Migration and Invasion of Human Glioblastoma Cells by Targeting Phosphorylated β-Catenin and Phosphorylated PI3K/Akt: A Potential Mechanism for the Anti-Glioma Efficacy of a Traditional Chinese Herbal Medicine. Int. J. Mol. Sci. 2015, 16, 23823–23848. International Journal of Molecular Sciences. 2025; 26(13):5922. https://doi.org/10.3390/ijms26135922

Chicago/Turabian Style

Zhang, Feng-Ying, Yi Hu, Zhong-You Que, Ping Wang, Yun-Hui Liu, Zhen-Hua Wang, and Yi-Xue Xue. 2025. "RETRACTED: Zhang et al. Shikonin Inhibits the Migration and Invasion of Human Glioblastoma Cells by Targeting Phosphorylated β-Catenin and Phosphorylated PI3K/Akt: A Potential Mechanism for the Anti-Glioma Efficacy of a Traditional Chinese Herbal Medicine. Int. J. Mol. Sci. 2015, 16, 23823–23848" International Journal of Molecular Sciences 26, no. 13: 5922. https://doi.org/10.3390/ijms26135922

APA Style

Zhang, F.-Y., Hu, Y., Que, Z.-Y., Wang, P., Liu, Y.-H., Wang, Z.-H., & Xue, Y.-X. (2025). RETRACTED: Zhang et al. Shikonin Inhibits the Migration and Invasion of Human Glioblastoma Cells by Targeting Phosphorylated β-Catenin and Phosphorylated PI3K/Akt: A Potential Mechanism for the Anti-Glioma Efficacy of a Traditional Chinese Herbal Medicine. Int. J. Mol. Sci. 2015, 16, 23823–23848. International Journal of Molecular Sciences, 26(13), 5922. https://doi.org/10.3390/ijms26135922

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop