Combination of Slightly Acidic Electrolyzed Water and Hydrogel to Enhance Stability, Increase Antibacterial Efficacy, and Promote Infectious Wound Healing
Abstract
1. Introduction
2. Results and Discussion
2.1. Properties of SAEW and SAEW-Gel
2.2. Evaluation of Antibacterial Activity In Vitro
2.3. Stability of SAEW-Gel
2.4. Evaluation of Promoting Healing Effect on Skin Wounds
2.5. Pathological Observation of Skin Wounds
2.6. Detection of Bacterial Load in Skin Wound
2.7. Determination of Inflammatory Factors, Anti-Inflammatory Factors, and Collagen in Skin Wound Tissue
3. Materials and Methods
3.1. Materials
3.2. Preparation of SAEW
3.3. Stability Investigation of SAEW
3.4. Preparation of SAEW-Gel
3.5. Appearance and SEM Observation of Gel
3.6. Antibacterial Effect In Vitro of SAEW-Gel
3.7. Swelling Test
3.8. Water Retention Test
3.9. Stability Investigation of SAEW-Gel
3.10. Evaluation of Promoting Healing Effect on Skin Wounds
4. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Li, N.; Li, C.; Li, D.; Abbas, A.; Chen, X.; Ai, X.; Zhang, W.; Shu, G.; Lin, J.; Li, H.; et al. Combination of Slightly Acidic Electrolyzed Water and Hydrogel to Enhance Stability, Increase Antibacterial Efficacy, and Promote Infectious Wound Healing. Int. J. Mol. Sci. 2025, 26, 5908. https://doi.org/10.3390/ijms26125908
Li N, Li C, Li D, Abbas A, Chen X, Ai X, Zhang W, Shu G, Lin J, Li H, et al. Combination of Slightly Acidic Electrolyzed Water and Hydrogel to Enhance Stability, Increase Antibacterial Efficacy, and Promote Infectious Wound Healing. International Journal of Molecular Sciences. 2025; 26(12):5908. https://doi.org/10.3390/ijms26125908
Chicago/Turabian StyleLi, Nanxin, Chao Li, Dongbo Li, Awn Abbas, Xingyu Chen, Xiaoyang Ai, Wei Zhang, Gang Shu, Juchun Lin, Haohuan Li, and et al. 2025. "Combination of Slightly Acidic Electrolyzed Water and Hydrogel to Enhance Stability, Increase Antibacterial Efficacy, and Promote Infectious Wound Healing" International Journal of Molecular Sciences 26, no. 12: 5908. https://doi.org/10.3390/ijms26125908
APA StyleLi, N., Li, C., Li, D., Abbas, A., Chen, X., Ai, X., Zhang, W., Shu, G., Lin, J., Li, H., Xu, F., Peng, G., & Fu, H. (2025). Combination of Slightly Acidic Electrolyzed Water and Hydrogel to Enhance Stability, Increase Antibacterial Efficacy, and Promote Infectious Wound Healing. International Journal of Molecular Sciences, 26(12), 5908. https://doi.org/10.3390/ijms26125908