Drosophila: A Versatile Model in Biology and Medicine
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References
- Perveen, F.K. Introduction to Drosophila. In Drosophila Melanogaster—Model for Recent Advances in Genetics and Therapeutics; InTech: Rang-Du-Fliers, France, 2018. [Google Scholar] [CrossRef]
- Kaufman, T.C. A Short History and Description of Drosophila melanogaster Classical Genetics: Chromosome Aberrations, Forward Genetic Screens, and the Nature of Mutations. Genetics 2017, 206, 665–689. [Google Scholar] [CrossRef] [PubMed]
- Morgan, T.H. Sex Limited Inheritance in Drosophila. Science 1910, 32, 120–122. [Google Scholar] [CrossRef] [PubMed]
- Vecchie’, D.; Wolter, J.M.; Perry, J.; Jumbo-Lucioni, P.; De Luca, M. The Impact of the Angiotensin-Converting Enzyme Inhibitor Lisinopril on Metabolic Rate in Drosophila melanogaster. Int. J. Mol. Sci. 2024, 25, 10103. [Google Scholar] [CrossRef] [PubMed]
- Steinmetz, E.L.; Scherer, A.; Calvet, C.; Müller, U. Orthologs of NOX5 and EC-SOD/SOD3: DNox and DSod3 Impact Egg Hardening Process and Egg Laying in Reproductive Function of Drosophila melanogaster. Int. J. Mol. Sci. 2024, 25, 6138. [Google Scholar] [CrossRef] [PubMed]
- Elovsson, G.; Klingstedt, T.; Brown, M.; Nilsson, K.P.R.; Brorsson, A.-C. A Novel Drosophila Model of Alzheimer’s Disease to Study Aβ Proteotoxicity in the Digestive Tract. Int. J. Mol. Sci. 2024, 25, 2105. [Google Scholar] [CrossRef] [PubMed]
- Chen, W.; Zhong, W.; Yu, L.; Lin, X.; Xie, J.; Liu, Z. A Drosophila Model Reveals the Potential Role for Mtt in Retinal Disease. Int. J. Mol. Sci. 2024, 25, 899. [Google Scholar] [CrossRef]
- Cheng, J.; Wu, B.-T.; Liu, H.-P.; Lin, W.-Y. Tyrosine Metabolism Pathway Is Downregulated in Dopaminergic Neurons with LRRK2 Overexpression in Drosophila. Int. J. Mol. Sci. 2023, 24, 15587. [Google Scholar] [CrossRef]
- Atienzar-Aroca, S.; Kat, M.; López-Castel, A. Decoding Nucleotide Repeat Expansion Diseases: Novel Insights from Drosophila melanogaster Studies. Int. J. Mol. Sci. 2024, 25, 11794. [Google Scholar] [CrossRef] [PubMed]
- Ehrhardt, B.; Roeder, T.; Krauss-Etschmann, S. Drosophila melanogaster as an Alternative Model to Higher Organisms for In Vivo Lung Research. Int. J. Mol. Sci. 2024, 25, 10324. [Google Scholar] [CrossRef] [PubMed]
- Volonté, C.; Liguori, F.; Amadio, S. A Closer Look at Histamine in Drosophila. Int. J. Mol. Sci. 2024, 25, 4449. [Google Scholar] [CrossRef] [PubMed]
- Vedelek, V.; Jankovics, F.; Zádori, J.; Sinka, R. Mitochondrial Differentiation during Spermatogenesis: Lessons from Drosophila melanogaster. Int. J. Mol. Sci. 2024, 25, 3980. [Google Scholar] [CrossRef] [PubMed]
- Melnikova, L.; Golovnin, A. Multiple Roles of DXNP and DADD1—Drosophila Orthologs of ATRX Chromatin Remodeler. Int. J. Mol. Sci. 2023, 24, 16486. [Google Scholar] [CrossRef] [PubMed]
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Giansanti, M.G.; Piergentili, R. Drosophila: A Versatile Model in Biology and Medicine. Int. J. Mol. Sci. 2025, 26, 5032. https://doi.org/10.3390/ijms26115032
Giansanti MG, Piergentili R. Drosophila: A Versatile Model in Biology and Medicine. International Journal of Molecular Sciences. 2025; 26(11):5032. https://doi.org/10.3390/ijms26115032
Chicago/Turabian StyleGiansanti, Maria Grazia, and Roberto Piergentili. 2025. "Drosophila: A Versatile Model in Biology and Medicine" International Journal of Molecular Sciences 26, no. 11: 5032. https://doi.org/10.3390/ijms26115032
APA StyleGiansanti, M. G., & Piergentili, R. (2025). Drosophila: A Versatile Model in Biology and Medicine. International Journal of Molecular Sciences, 26(11), 5032. https://doi.org/10.3390/ijms26115032