In the original publication [1], there was a mistake in Figure 3 as published. The bar graphs in A, C, E, F, H, I, and J were missing the asterisks denoting the statistical significance of the pairwise comparison in correspondence to the p values in the figure legend. The corrected Figure 3 appears below. The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.
Figure 3.
Effect and inter-regulation of KLF2 and KLF4 on CMEC function. (A) Analysis of 6 h open wound areas in percentage in MCMECs upon knockdown of Klf2 or Klf4 (n = 4). (B) Bright field images using a Cytation 1 plate reader of MCMEC migration at 0 and 6 h upon knockdown of Klf2. Scale bars equal 1 mm. Quantitative PCR analysis of (C) Klf4 gene expression upon knockdown of Klf2 in MCMECs and (D) Klf2 gene expression upon knockdown of Klf4 in MCMECs, each compared to respective controls (n = 4). (E,F) Quantitative PCR analysis of (E) KLF2 and (F) KLF4 in diabetic HCMECs upon miR-92a inhibition by antagomir (Ant-92a) relative to controls (Ant-Ctrl) (n = 6) and (G) KLF2 and (H) KLF4 in nondiabetic HCMECs upon miR-92a overexpression (pre-92a) relative to controls (pre-Ctrl) (n = 4). (I,J) Quantitative PCR analysis of (I) KLF2 and (J) KLF4 in HUVECs upon miR-92a overexpression (pre-92a) relative to controls (pre-Ctrl). Statistical analyses by unpaired Student’s t-test or by one-way ANOVA (n ≥ 4); * p < 0.05; ** p < 0.01; **** p < 0.0001; ns: not significant.
Reference
- Samak, M.; Kues, A.; Kaltenborn, D.; Klösener, L.; Mietsch, M.; Germena, G.; Hinkel, R. Dysregulation of Krüppel-like Factor 2 and Myocyte Enhancer Factor 2D Drive Cardiac Microvascular Inflammation and Dysfunction in Diabetes. Int. J. Mol. Sci. 2023, 24, 2482. [Google Scholar] [CrossRef] [PubMed]
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