Mesenchymal Stem Cells and Their Exocytotic Vesicles
Round 1
Reviewer 1 Report
I commend the authors for their review on various applications of Mesenchymal stem cells(MSCs) that has been used in current tissue engineering and regeneration arena. The manuscript is well written. Categorizing the MSCs applications according to area of study/research is a plus to this manuscript. Both current (articles published within past five years) and past (articles that were published more than five years ago) were effectively utilized to state the uses/applications of MSCs. Summary and perspective section provided a thorough gist of all the applications and potential problems that need to be addressed. I would suggest publishing this article in its current state.
Author Response
Dear reviewer:
Thank you very much for your comments and recognition on our manuscript.
Out of motivation and responsibility for your approval, we have carefully combed through the entire manuscript twice to find and correct some errors and problems for a better reading experience.
Thank you very much for your attention and time.
Best wishes.
Hai-dong Guo
Reviewer 2 Report
The manuscript is overall well written.
I suggest to add a specific paragraph on cytokines and improve the paragraph on mesenchymal stem cells.
Additionally, I suggest to improve the quality of figure 1.
Author Response
Dear reviewer:
Thank you so much four your comments and professional advice concerning our manuscript entitled “Mesenchymal stem cells and their exocytotic vesicles”. These opinions help to improve academic and rigor of our article. Based on your suggestion and request, we have made correct modifications on the revised manuscript. The responses to your comments are as follows:
The manuscript is overall well written.
Response: Thank you so much for your positive comment.
I suggest to add a specific paragraph on cytokines and improve the paragraph on mesenchymal stem cells.
Response: We gratefully thanks for the precious time you spent making constructive remarks of our review. We have added a paragraph on cytokines before the sixth part summary and prospect. In addition, we have made multiple changes to the MSC paragraph, which you can see in Part I MSC.
Additionally, I suggest to improve the quality of figure 1.
Response: Thank you for your rigorous consideration. We changed the drawing tool and remade the figure 1.
Once again, thank you very much for your constructive comments and suggestions which would help us both in English and in depth to improve the quality of the paper.
Kind regards.
Hai-dong Guo
