MicroRNAs as the Sentinels of Redox and Hypertrophic Signalling
Abstract
:1. Introduction
1.1. Challenging the Oxidative Stress Theory of Muscular Function Decline
1.2. miRNA Memory Cloud Perpetuates the Exercise-Induced Adaptive Phenotype
1.3. Role of miRNAs in Myogenesis—The Orchestration of the Metabolic Symphony
1.4. The Role of miRNA Networks in Muscle and Metabolic Health—The Context Matters as Much as the Content
1.5. Muscle miRNA Networks in Metabolic Disease, Ageing and Exercise Training—Fine-Tuning Thermostat of Redox and Anabolic Sensitivity
1.6. Chronic Endurance Training-Induced miRNA Cloud and the Adaptation-Permissive Epigenetic Landscape—Revised Molecular Basis of Exercise Adaptation Model
1.7. Circulating miRNAs as the Universal Language of the Hormesis Response—Biomarkers of Systemic Metabolic Health and Adaptability
2. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Kolodziej, F.; McDonagh, B.; Burns, N.; Goljanek-Whysall, K. MicroRNAs as the Sentinels of Redox and Hypertrophic Signalling. Int. J. Mol. Sci. 2022, 23, 14716. https://doi.org/10.3390/ijms232314716
Kolodziej F, McDonagh B, Burns N, Goljanek-Whysall K. MicroRNAs as the Sentinels of Redox and Hypertrophic Signalling. International Journal of Molecular Sciences. 2022; 23(23):14716. https://doi.org/10.3390/ijms232314716
Chicago/Turabian StyleKolodziej, Filip, Brian McDonagh, Nicole Burns, and Katarzyna Goljanek-Whysall. 2022. "MicroRNAs as the Sentinels of Redox and Hypertrophic Signalling" International Journal of Molecular Sciences 23, no. 23: 14716. https://doi.org/10.3390/ijms232314716