Na+/K+- and Mg2+-ATPases and Their Interaction with AMPA, NMDA and D2 Dopamine Receptors in an Animal Model of Febrile Seizures
Abstract
:1. Introduction
2. Results
2.1. Na+/K+-ATPase Activity in Cortical Plasma Membranes after HIS
2.2. Modulation of Na+/K+-ATPase Activity by G-Protein-Coupled Receptor after HIS
2.3. Modulation of Na+/K+-ATPase Activity by Ionotropic Glutamate Receptor after HIS
2.4. Modulation of Na+/K+-ATPase Activity after HIS by AMPA and Sumanirole in 2-Month-Old Animals
2.5. Mg2+-ATPase Activity in Cortical Plasma Membrane after HIS
2.6. Modulation of Mg2+-ATPase Activity by G-Protein-Coupled Receptor after HIS
2.7. Modulation of Mg2+-ATPase by Ionotropic Receptors after HIS
2.8. Protein Level of Na+/K+ATPase and Receptors after HIS
3. Discussion
4. Materials and Methods
4.1. Materials
4.2. Animals
4.3. Hyperthermia-Induced Seizures
4.4. Cerebral Cortical Membrane Isolation
4.5. Na+/K+-ATPase and Mg2+-ATPase Activities Assay
4.6. Western-Blotting Assay
4.7. Statistical and Data Analysis
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Conflicts of Interest
References
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Crespo, M.; León-Navarro, D.A.; Martín, M. Na+/K+- and Mg2+-ATPases and Their Interaction with AMPA, NMDA and D2 Dopamine Receptors in an Animal Model of Febrile Seizures. Int. J. Mol. Sci. 2022, 23, 14638. https://doi.org/10.3390/ijms232314638
Crespo M, León-Navarro DA, Martín M. Na+/K+- and Mg2+-ATPases and Their Interaction with AMPA, NMDA and D2 Dopamine Receptors in an Animal Model of Febrile Seizures. International Journal of Molecular Sciences. 2022; 23(23):14638. https://doi.org/10.3390/ijms232314638
Chicago/Turabian StyleCrespo, María, David Agustín León-Navarro, and Mairena Martín. 2022. "Na+/K+- and Mg2+-ATPases and Their Interaction with AMPA, NMDA and D2 Dopamine Receptors in an Animal Model of Febrile Seizures" International Journal of Molecular Sciences 23, no. 23: 14638. https://doi.org/10.3390/ijms232314638