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10.3390/ijms232012706
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Review

Phase Behavior of Ionic Liquid-Based Aqueous Two-Phase Systems

by
Lirong Nie
1,
Ziwei Zheng
1,
Mingxia Lu
1,
Shun Yao
2 and
Dong Guo
1,*
1
School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China
2
School of Chemical Engineering, Sichuan University, Chengdu 610065, China
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2022, 23(20), 12706; https://doi.org/10.3390/ijms232012706
Submission received: 25 July 2022 / Revised: 6 October 2022 / Accepted: 14 October 2022 / Published: 21 October 2022
(This article belongs to the Special Issue Macroscopic and Microscopic Thermodynamics: From Fundamentals to Present Applications 2.0)
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Abstract

As an environmentally friendly separation medium, the ionic liquid (IL)-based aqueous two-phase system (ATPS) is attracting long-term attention from a growing number of scientists and engineers. Phase equilibrium data of IL-based ATPSs are an important basis for the design and optimization of chemical reactions and separation processes involving ILs. This article provides the recent significant progress that has been made in the field and highlights the possible directions of future developments. The effects of each component (such as salting-out agents and ILs) on the phase behavior of IL-based ATPSs are summarized and discussed in detail. We mainly focus on the phase behavior of ATPSs by using ILs, expecting to provide meaningful and valuable information that may promote further research and application.
Keywords: phase equilibrium; ionic liquid; aqueous two-phase system; salting-out agent; mechanism phase equilibrium; ionic liquid; aqueous two-phase system; salting-out agent; mechanism

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MDPI and ACS Style

Nie, L.; Zheng, Z.; Lu, M.; Yao, S.; Guo, D. Phase Behavior of Ionic Liquid-Based Aqueous Two-Phase Systems. Int. J. Mol. Sci. 2022, 23, 12706. https://doi.org/10.3390/ijms232012706

AMA Style

Nie L, Zheng Z, Lu M, Yao S, Guo D. Phase Behavior of Ionic Liquid-Based Aqueous Two-Phase Systems. International Journal of Molecular Sciences. 2022; 23(20):12706. https://doi.org/10.3390/ijms232012706

Chicago/Turabian Style

Nie, Lirong, Ziwei Zheng, Mingxia Lu, Shun Yao, and Dong Guo. 2022. "Phase Behavior of Ionic Liquid-Based Aqueous Two-Phase Systems" International Journal of Molecular Sciences 23, no. 20: 12706. https://doi.org/10.3390/ijms232012706

APA Style

Nie, L., Zheng, Z., Lu, M., Yao, S., & Guo, D. (2022). Phase Behavior of Ionic Liquid-Based Aqueous Two-Phase Systems. International Journal of Molecular Sciences, 23(20), 12706. https://doi.org/10.3390/ijms232012706

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