Epigenetic Regulation in Neurodegeneration Disease
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References
- Crapper, D.R.; Quittkat, S.; de Boni, U. Altered Chromatin Conformation in Alzheimer’s Disease. Brain 1979, 102, 483–495. [Google Scholar] [CrossRef] [PubMed]
- Steffan, J.S.; Bodai, L.; Pallos, J.; Poelman, M.; McCampbell, A.; Apostol, B.L.; Kazantsev, A.; Schmidt, E.; Zhu, Y.Z.; Greenwald, M.; et al. Histone Deacetylase Inhibitors Arrest Polyglutamine-Dependent Neurodegeneration in Drosophila. Nature 2001, 413, 739–743. [Google Scholar] [CrossRef] [PubMed]
- Bankole, O.; Scambi, I.; Parrella, E.; Muccilli, M.; Bonafede, R.; Turano, E.; Pizzi, M.; Mariotti, R. Beneficial and Sexually Dimorphic Response to Combined HDAC Inhibitor Valproate and AMPK/SIRT1 Pathway Activator Resveratrol in the Treatment of ALS Mice. Int. J. Mol. Sci. 2022, 23, 1047. [Google Scholar] [CrossRef] [PubMed]
- Frankowski, H.; Yeboah, F.; Berry, B.J.; Kinoshita, C.; Lee, M.; Evitts, K.; Davis, J.; Kinoshita, Y.; Morrison, R.S.; Young, J.E. Knock-Down of HDAC2 in Human Induced Pluripotent Stem Cell Derived Neurons Improves Neuronal Mitochondrial Dynamics, Neuronal Maturation and Reduces Amyloid Beta Peptides. Int. J. Mol. Sci. 2021, 22, 2526. [Google Scholar] [CrossRef] [PubMed]
- Tan, Y.; Delvaux, E.; Nolz, J.; Coleman, P.D.; Chen, S.; Mastroeni, D. Upregulation of Histone Deacetylase 2 in Laser Capture Nigral Microglia in Parkinson’s Disease. Neurobiol. Aging 2018, 68, 134–141. [Google Scholar] [CrossRef] [PubMed]
- Mahady, L.; Nadeem, M.; Malek-Ahmadi, M.; Chen, K.; Perez, S.E.; Mufson, E.J. HDAC2 Dysregulation in the Nucleus Basalis of Meynert during the Progression of Alzheimer’s Disease. Neuropathol. Appl. Neurobiol. 2019, 45, 380–397. [Google Scholar] [CrossRef] [PubMed]
- Puente-Bedia, A.; Berciano, M.T.; Tapia, O.; Martínez-Cué, C.; Lafarga, M.; Rueda, N. Nuclear Reorganization in Hippocampal Granule Cell Neurons from a Mouse Model of Down Syndrome: Changes in Chromatin Configuration, Nucleoli and Cajal Bodies. Int. J. Mol. Sci. 2021, 22, 1259. [Google Scholar] [CrossRef] [PubMed]
- Basavarajappa, B.S.; Subbanna, S. Histone Methylation Regulation in Neurodegenerative Disorders. Int. J. Mol. Sci. 2021, 22, 4654. [Google Scholar] [CrossRef] [PubMed]
- Zsindely, N.; Siági, F.; Bodai, L. DNA Methylation in Huntington’s Disease. Int. J. Mol. Sci. 2021, 22, 12736. [Google Scholar] [CrossRef]
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Bodai, L. Epigenetic Regulation in Neurodegeneration Disease. Int. J. Mol. Sci. 2022, 23, 6185. https://doi.org/10.3390/ijms23116185
Bodai L. Epigenetic Regulation in Neurodegeneration Disease. International Journal of Molecular Sciences. 2022; 23(11):6185. https://doi.org/10.3390/ijms23116185
Chicago/Turabian StyleBodai, László. 2022. "Epigenetic Regulation in Neurodegeneration Disease" International Journal of Molecular Sciences 23, no. 11: 6185. https://doi.org/10.3390/ijms23116185
APA StyleBodai, L. (2022). Epigenetic Regulation in Neurodegeneration Disease. International Journal of Molecular Sciences, 23(11), 6185. https://doi.org/10.3390/ijms23116185