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In Pursuit of Healthy Aging: Effects of Nutrition on Brain Function

1
Neuroscience Graduate Program, Federal University of Santa Catarina, Florianópolis 88040-900, SC, Brazil
2
Translational Psychiatry Laboratory, Graduate Program in Health Sciences, University of Southern Santa Catarina, Criciúma 88806-000, SC, Brazil
3
Department of Rehabilitation Sciences, Hong Kong Polytechnic University, Hung Hom, Hong Kong, China
4
Division of Medical Sciences, University of Victoria, Victoria, BC V8P 5C2, Canada
5
Island Medical Program, Faculty of Medicine, University of British Columbia, Victoria, BC V8P 5C2, Canada
*
Authors to whom correspondence should be addressed.
Academic Editor: Fabien Pifferi
Int. J. Mol. Sci. 2021, 22(9), 5026; https://doi.org/10.3390/ijms22095026
Received: 13 April 2021 / Revised: 5 May 2021 / Accepted: 6 May 2021 / Published: 10 May 2021
(This article belongs to the Special Issue The Links between Nutrition, Energy Metabolism, Aging and Cognition)
Consuming a balanced, nutritious diet is important for maintaining health, especially as individuals age. Several studies suggest that consuming a diet rich in antioxidants and anti-inflammatory components such as those found in fruits, nuts, vegetables, and fish may reduce age-related cognitive decline and the risk of developing various neurodegenerative diseases. Numerous studies have been published over the last decade focusing on nutrition and how this impacts health. The main objective of the current article is to review the data linking the role of diet and nutrition with aging and age-related cognitive decline. Specifically, we discuss the roles of micronutrients and macronutrients and provide an overview of how the gut microbiota-gut-brain axis and nutrition impact brain function in general and cognitive processes in particular during aging. We propose that dietary interventions designed to optimize the levels of macro and micronutrients and maximize the functioning of the microbiota-gut-brain axis can be of therapeutic value for improving cognitive functioning, particularly during aging. View Full-Text
Keywords: aging; cognition; macronutrients; microbiota-gut-brain axis; micronutrients; neurodegeneration; nutrition aging; cognition; macronutrients; microbiota-gut-brain axis; micronutrients; neurodegeneration; nutrition
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MDPI and ACS Style

Melzer, T.M.; Manosso, L.M.; Yau, S.-y.; Gil-Mohapel, J.; Brocardo, P.S. In Pursuit of Healthy Aging: Effects of Nutrition on Brain Function. Int. J. Mol. Sci. 2021, 22, 5026. https://doi.org/10.3390/ijms22095026

AMA Style

Melzer TM, Manosso LM, Yau S-y, Gil-Mohapel J, Brocardo PS. In Pursuit of Healthy Aging: Effects of Nutrition on Brain Function. International Journal of Molecular Sciences. 2021; 22(9):5026. https://doi.org/10.3390/ijms22095026

Chicago/Turabian Style

Melzer, Thayza M., Luana M. Manosso, Suk-yu Yau, Joana Gil-Mohapel, and Patricia S. Brocardo 2021. "In Pursuit of Healthy Aging: Effects of Nutrition on Brain Function" International Journal of Molecular Sciences 22, no. 9: 5026. https://doi.org/10.3390/ijms22095026

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