The authors wish to make the following corrections to paper “DNA Methylation Analysis Identifies Patterns in Progressive Glioma Grades to Predict Patient Survival” [1
In Figure 4C, the p
-value for the Fn14
(cg00510447) box plot is incorrect. Figure 4 should be replaced with the following figure (Figure 1
In Figure 6, the methylation status requirement shown in the schematic diagram is reversed but the subsequent analysis is not impacted. Figure 6 should be replaced with the following figure (Figure 2
In the main text, there was an error in Paragraph 1, 3rd sentence of Section 2.1. The definition of hypo- and hypermethylated CpG sites outputted from the differential variability analysis is an inexact description. A correction has been made to this as presented below:
In the comparison between Grade II and Grade III gliomas, 2095 and 146 CpG sites (1.54 × 10−10 ≤ p-value ≤ 0.00062, 2.75 × 10−5 ≤ false discovery rate (FDR) ≤ 0.05) were methylated at a consistent level in one glioma grade, while the other glioma grade shows hypo- or hypermethylation variability (Figure 1A).
The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original article has been updated.