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Open AccessArticle

One Pot Synthesis of Large Gold Nanoparticles with Triple Functional Ferrocene Ligands

1
School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, China
2
Key Laboratory for Water Quality and Conservation of the Pearl River Delta, Institute of Environmental Research at Greater Bay, Ministry of Education, Guangzhou University, Guangzhou 510006, China
*
Author to whom correspondence should be addressed.
Academic Editor: Ana María Díez-Pascual
Int. J. Mol. Sci. 2021, 22(5), 2328; https://doi.org/10.3390/ijms22052328
Received: 1 January 2021 / Revised: 22 February 2021 / Accepted: 23 February 2021 / Published: 26 February 2021
(This article belongs to the Collection Bioactive Nanoparticles)
In biomedical, toxicological, and optoelectronic applications, the size of nanoparticles is one of the decisive factors. Therefore, synthesis of nanoparticles with controlled sizes is required. The current methods for synthesis of larger gold nanoparticles (GNPs, ~200 nm) are complex and tedious, producing nanoparticles with a lower yield and more irregular shapes. Using ferrocene as a primary reducing agent and stabilizer, sodium citrate as a dispersant, and sodium borohydride as an accessory reducing agent, GNPs of 200 nm were synthesized in a one pot reaction. Besides the roles of reducing agent and GNP stabilizer, ferrocene also served a role of quantitative marker for ligand loading, allowing an accurate determinate of surface ligands. View Full-Text
Keywords: stepwise synthesis; ferrocene derivatives; rapid quantification of ligands; low cytotoxicity GNPs stepwise synthesis; ferrocene derivatives; rapid quantification of ligands; low cytotoxicity GNPs
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MDPI and ACS Style

Wang, S.; Liu, F.; Liu, Y.; Zhou, H.; Yan, B. One Pot Synthesis of Large Gold Nanoparticles with Triple Functional Ferrocene Ligands. Int. J. Mol. Sci. 2021, 22, 2328. https://doi.org/10.3390/ijms22052328

AMA Style

Wang S, Liu F, Liu Y, Zhou H, Yan B. One Pot Synthesis of Large Gold Nanoparticles with Triple Functional Ferrocene Ligands. International Journal of Molecular Sciences. 2021; 22(5):2328. https://doi.org/10.3390/ijms22052328

Chicago/Turabian Style

Wang, Shenqing; Liu, Fang; Liu, Yin; Zhou, Hongyu; Yan, Bing. 2021. "One Pot Synthesis of Large Gold Nanoparticles with Triple Functional Ferrocene Ligands" Int. J. Mol. Sci. 22, no. 5: 2328. https://doi.org/10.3390/ijms22052328

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