Bone Regeneration of a 3D-Printed Alloplastic and Particulate Xenogenic Graft with rhBMP-2
Abstract
:1. Introduction
2. Results
2.1. Architecture of Scaffold
2.2. Cytotoxicity Test
2.3. Clinical Findings
2.4. Radiological Evaluation
2.5. Histological Evaluation
3. Discussion
4. Materials and Methods
4.1. Subject
4.2. Preparation of Scaffolds
4.3. Cytotoxic Tests
4.4. Surgical Procedures
4.5. Analysis
4.5.1. Radiological Examination
4.5.2. Histological Examination
4.5.3. Statistical Analysis
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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N Group | P Group | 3D Group | Difference (p) | ||
---|---|---|---|---|---|
6 weeks | New bone (%) | 21.57 ± 1.86 | 32.63 ± 7.06 | 29.57 ± 9.41 | 0.041 * |
Total bone (%) | 21.57 ± 1.86 | 34.89 ± 6.25 | 30.50 ± 9.81 | 0.033 * | |
12 weeks | New bone (%) | 27.51 ± 14.22 | 45.49 ± 12.09 | 43.79 ± 19.35 | 0.073 |
Total bone (%) | 27.51 ± 14.22 | 49.22 ± 14.33 | 45.70 ± 19.39 | 0.039 * |
N Group | P Group | 3D Group | Difference (p) | ||
---|---|---|---|---|---|
6 weeks | New bone (%) | 21.56 ± 1.84 | 25.25 ± 6.49 | 23.90 ± 9.57 | 0.365 |
Total bone (%) | 21.56 ± 1.84 | 32.38 ± 7.68 | 27.81 ± 6.73 | 0.013 * | |
12 weeks | New bone (%) | 25.42 ± 14.27 | 30.54 ± 14.92 | 39.54 ± 7.83 | 0.065 |
Total bone (%) | 25.42 ± 14.27 | 39.32 ± 12.16 | 43.01 ± 8.23 | 0.026 * |
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Ryu, J.-I.; Yang, B.-E.; Yi, S.-M.; Choi, H.G.; On, S.-W.; Hong, S.J.; Lim, H.-K.; Byun, S.-H. Bone Regeneration of a 3D-Printed Alloplastic and Particulate Xenogenic Graft with rhBMP-2. Int. J. Mol. Sci. 2021, 22, 12518. https://doi.org/10.3390/ijms222212518
Ryu J-I, Yang B-E, Yi S-M, Choi HG, On S-W, Hong SJ, Lim H-K, Byun S-H. Bone Regeneration of a 3D-Printed Alloplastic and Particulate Xenogenic Graft with rhBMP-2. International Journal of Molecular Sciences. 2021; 22(22):12518. https://doi.org/10.3390/ijms222212518
Chicago/Turabian StyleRyu, Ji-In, Byoung-Eun Yang, Sang-Min Yi, Hyo Geun Choi, Sung-Woon On, Seok Jin Hong, Ho-Kyung Lim, and Soo-Hwan Byun. 2021. "Bone Regeneration of a 3D-Printed Alloplastic and Particulate Xenogenic Graft with rhBMP-2" International Journal of Molecular Sciences 22, no. 22: 12518. https://doi.org/10.3390/ijms222212518