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Volume 22
Issue 15
10.3390/ijms22158269
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Review
Peer-Review Record

Metabolic Swifts Govern Normal and Malignant B Cell Lymphopoiesis

Int. J. Mol. Sci. 2021, 22(15), 8269; https://doi.org/10.3390/ijms22158269
by Aikaterini Poulaki 1,2 and Stavroula Giannouli 2,*
Reviewer 1: Anonymous
Reviewer 2: Anonymous
Int. J. Mol. Sci. 2021, 22(15), 8269; https://doi.org/10.3390/ijms22158269
Submission received: 7 July 2021 / Revised: 24 July 2021 / Accepted: 28 July 2021 / Published: 31 July 2021
(This article belongs to the Special Issue Metabolic Disturbances in Hematologic Malignancies)

Round 1

Reviewer 1 Report

In my opinion this is a very good and needed paper, I do congratulate the Authors. I believe that this kind of a review paper is needed to comprehensively summarize the state of knowledge on malignant metabolism.

I do recommend the paper to be published in its present form.

Author Response

Response to Reviewer I:

Comment: In my opinion this is a very good and needed paper, I do congratulate the Authors. I believe that this kind of a review paper is needed to comprehensively summarize the state of knowledge on malignant metabolism.

I do recommend the paper to be published in its present form.

Response: We thank you for your positive feedback on our work. We truly appreciate your response.

Reviewer 2 Report

In this article, the authors comprehensively elaborated the metabolic swifts that govern normal B cell lymphopoiesis examining malignant metabolism in an attempt to uncover new research goals and therapeutic targets. It is well compiled and the illustrations are quite informative.

However, paragraph 2.1.1 and paragraph 2.2. are long and difficult to understand. 

Since the topic of the review is quite complicated, I would suggest breaking down these paragraphs and trying to make it more understandable.

 

Author Response

Response to reviewer II:

Comment: In this article, the authors comprehensively elaborated the metabolic swifts that govern normal B cell lymphopoiesis examining malignant metabolism in an attempt to uncover new research goals and therapeutic targets. It is well compiled and the illustrations are quite informative.

However, paragraph 2.1.1 and paragraph 2.2. are long and difficult to understand.

Since the topic of the review is quite complicated, I would suggest breaking down these paragraphs and trying to make it more understandable.

Response: Thank you for the constructive criticism. We did our best to address all your concerns. Please see the revised version of the manuscript in regards of paragraph division and entitlement.

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