Role of Polycomb Complexes in Normal and Malignant Plasma Cells
Abstract
:1. Introduction
2. PcG Complexes
3. Lymphopoiesis and Plasma Cell Differentiation
3.1. PcG Proteins and Early B Cell Differentiation
3.2. PcG Proteins and the Primary Extra-Follicular Response
3.3. PcG Proteins and the Follicular Response
3.4. PcG Proteins and the Secondary Extra-Follicular Response
4. Multiple Myeloma
4.1. PRC2 in Multiple Myeloma Pathophysiology
4.2. PRC1 in Multiple Myeloma Pathophysiology
4.3. PcG Proteins and Multiple Myeloma Tumor Microenvironment
4.4. PcG Proteins and Drug Resistance in Multiple Myeloma
5. Concluding Remarks
Author Contributions
Funding
Conflicts of Interest
References
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Varlet, E.; Ovejero, S.; Martinez, A.-M.; Cavalli, G.; Moreaux, J. Role of Polycomb Complexes in Normal and Malignant Plasma Cells. Int. J. Mol. Sci. 2020, 21, 8047. https://doi.org/10.3390/ijms21218047
Varlet E, Ovejero S, Martinez A-M, Cavalli G, Moreaux J. Role of Polycomb Complexes in Normal and Malignant Plasma Cells. International Journal of Molecular Sciences. 2020; 21(21):8047. https://doi.org/10.3390/ijms21218047
Chicago/Turabian StyleVarlet, Emmanuel, Sara Ovejero, Anne-Marie Martinez, Giacomo Cavalli, and Jerome Moreaux. 2020. "Role of Polycomb Complexes in Normal and Malignant Plasma Cells" International Journal of Molecular Sciences 21, no. 21: 8047. https://doi.org/10.3390/ijms21218047
APA StyleVarlet, E., Ovejero, S., Martinez, A.-M., Cavalli, G., & Moreaux, J. (2020). Role of Polycomb Complexes in Normal and Malignant Plasma Cells. International Journal of Molecular Sciences, 21(21), 8047. https://doi.org/10.3390/ijms21218047