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Small RNAs, Big Diseases

by Iwona Rzeszutek 1,* and Aditi Singh 2,*
1
Institute of Biology and Biotechnology, Department of Biotechnology, University of Rzeszow, Pigonia 1, 35-310 Rzeszow, Poland
2
Max Planck Institute for Developmental Biology, Max-Planck-Ring 5, 72076 Tübingen, Germany
*
Authors to whom correspondence should be addressed.
Int. J. Mol. Sci. 2020, 21(16), 5699; https://doi.org/10.3390/ijms21165699
Received: 27 July 2020 / Revised: 6 August 2020 / Accepted: 8 August 2020 / Published: 9 August 2020
(This article belongs to the Special Issue RNA Regulatory Networks at the Crossroad of Human Diseases)
The past two decades have seen extensive research done to pinpoint the role of microRNAs (miRNAs) that have led to discovering thousands of miRNAs in humans. It is not, therefore, surprising to see many of them implicated in a number of common as well as rare human diseases. In this review article, we summarize the progress in our understanding of miRNA-related research in conjunction with different types of cancers and neurodegenerative diseases, as well as their potential in generating more reliable diagnostic and therapeutic approaches. View Full-Text
Keywords: noncoding RNA; miRNAs; chromosome fragile sites (CFSs); chromosome rearrangements; diseases noncoding RNA; miRNAs; chromosome fragile sites (CFSs); chromosome rearrangements; diseases
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Rzeszutek, I.; Singh, A. Small RNAs, Big Diseases. Int. J. Mol. Sci. 2020, 21, 5699.

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