Cadmium and Lead Decrease Cell–Cell Aggregation and Increase Migration and Invasion in Renca Mouse Renal Cell Carcinoma Cells
Abstract
:1. Introduction
2. Results
2.1. Impact of Cadmium and Lead on Renca Cell Viability
2.2. Impact of Cadmium and Lead on Cadherin and Catenin Expression
2.3. Impact of Cadmium and Lead on MMP-9 Expression
2.4. Impact of Cadmium and Lead on Renca cell Adhesion, Migration and Invasion
3. Discussion
4. Materials and Methods
4.1. Cell Lines
4.2. Cell Viability
4.3. Western Blot
4.4. Cell Aggregation
4.5. Wound Healing
4.6. Cell Migration and Invasion
4.7. Statistics
Author Contributions
Funding
Conflicts of Interest
References
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Akin, R.; Hannibal, D.; Loida, M.; Stevens, E.M.; Grunz-Borgmann, E.A.; Parrish, A.R. Cadmium and Lead Decrease Cell–Cell Aggregation and Increase Migration and Invasion in Renca Mouse Renal Cell Carcinoma Cells. Int. J. Mol. Sci. 2019, 20, 6315. https://doi.org/10.3390/ijms20246315
Akin R, Hannibal D, Loida M, Stevens EM, Grunz-Borgmann EA, Parrish AR. Cadmium and Lead Decrease Cell–Cell Aggregation and Increase Migration and Invasion in Renca Mouse Renal Cell Carcinoma Cells. International Journal of Molecular Sciences. 2019; 20(24):6315. https://doi.org/10.3390/ijms20246315
Chicago/Turabian StyleAkin, Ryan, David Hannibal, Margaret Loida, Emily M. Stevens, Elizabeth A. Grunz-Borgmann, and Alan R. Parrish. 2019. "Cadmium and Lead Decrease Cell–Cell Aggregation and Increase Migration and Invasion in Renca Mouse Renal Cell Carcinoma Cells" International Journal of Molecular Sciences 20, no. 24: 6315. https://doi.org/10.3390/ijms20246315