n-Butylamine for Improving the Efficiency of Untargeted Mass Spectrometry Analysis of Plasma Metabolite Composition
Abstract
:1. Introduction
2. Results
3. Discussion
4. Material and Methods
4.1. Blood Plasma Sample Preparation
4.2. Mass Spectrometry Analysis of Blood Plasma Metabolome
4.3. Data Analysis
4.4. Mass Spectra Peak Annotation
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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No. | Metabolites | HMDB ID | m/z Value | Elemental Composition | |
---|---|---|---|---|---|
Measured (m/z) | Calculated (Da) | ||||
1 | succinic acid | HMDB0000254 | 117.0195 | 117.0182 | C4H6O4 |
2 | malic acid | HMDB0000744 | 133.0157 | 133.0131 | C4H6O5 |
3 | palmitic acid | HMDB0000220 | 255.2405 | 255.2318 | C16H32O2 |
4 | α-linolenic acid | HMDB0001388 | 277.2201 | 277.2162 | C18H30O2 |
5 | arachidonic acid | HMDB0001043 | 303.2324 | 303.2318 | C20H32O2 |
6 | docosahexaenoic acid | HMDB0002183 | 327.2323 | 327.2318 | C22H32O2 |
7 | PG * | n/a | 735.5201 | 735.5170 | C39H77O10P |
8 | PG/PA * | n/a | 747.5201 | 747.5170 | C40H77O10P |
9 | PS * | n/a | 808.5143 | 808.5123 | C44H76NO10P |
10 | PS * | n/a | 830.5935 | 830.5905 | C45H86NO10P |
11 | n/a | n/a | 936.5211 | n/a | n/a |
12 | n/a | n/a | 938.5012 | n/a | n/a |
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Maslov, D.L.; Trifonova, O.P.; Balashova, E.E.; Lokhov, P.G. n-Butylamine for Improving the Efficiency of Untargeted Mass Spectrometry Analysis of Plasma Metabolite Composition. Int. J. Mol. Sci. 2019, 20, 5957. https://doi.org/10.3390/ijms20235957
Maslov DL, Trifonova OP, Balashova EE, Lokhov PG. n-Butylamine for Improving the Efficiency of Untargeted Mass Spectrometry Analysis of Plasma Metabolite Composition. International Journal of Molecular Sciences. 2019; 20(23):5957. https://doi.org/10.3390/ijms20235957
Chicago/Turabian StyleMaslov, Dmitry L., Oxana P. Trifonova, Elena E. Balashova, and Petr G. Lokhov. 2019. "n-Butylamine for Improving the Efficiency of Untargeted Mass Spectrometry Analysis of Plasma Metabolite Composition" International Journal of Molecular Sciences 20, no. 23: 5957. https://doi.org/10.3390/ijms20235957