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Clinical and Physiological Perspectives of β-Glucans: The Past, Present, and Future

Seafood Research Center, IACF, Silla University, Advanced Seafood Processing Complex #606, Wonyang-ro, Amnam-dong, Seo-gu, Busan 49277, Korea
Major in Food Biotechnology, Division of Bioindustry, College of Medical and Life Sciences, Silla University, 140, Baegyang-daero 700 beon-gil, Sasang-gu, Busan 46958, Korea
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2017, 18(9), 1906;
Received: 11 August 2017 / Revised: 31 August 2017 / Accepted: 31 August 2017 / Published: 5 September 2017
(This article belongs to the Special Issue Glucan: New Perspectives on Biochemistry and Application)
PDF [590 KB, uploaded 8 September 2017]


β-Glucans are a group of biologically-active fibers or polysaccharides from natural sources with proven medical significance. β-Glucans are known to have antitumor, anti-inflammatory, anti-obesity, anti-allergic, anti-osteoporotic, and immunomodulating activities. β-Glucans are natural bioactive compounds and can be taken orally, as a food supplement, or as part of a daily diet, and are considered safe to use. The medical significance and efficiency of β-glucans are confirmed in vitro, as well as using animal- and human-based clinical studies. However, systematic study on the clinical and physiological significance of β-glucans is scarce. In this review, we not only discuss the clinical and physiological importance of β-glucans, we also compare their biological activities through the existing in vitro and animal-based in vivo studies. This review provides extensive data on the clinical study of β-glucans. View Full-Text
Keywords: anti-obesity; anti-osteoporosis; antitumor; β-glucans; bioactive polysaccharides; immunomodulation anti-obesity; anti-osteoporosis; antitumor; β-glucans; bioactive polysaccharides; immunomodulation

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Bashir, K.M.I.; Choi, J.-S. Clinical and Physiological Perspectives of β-Glucans: The Past, Present, and Future. Int. J. Mol. Sci. 2017, 18, 1906.

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