Nerve Growth Factor and Related Substances: A Brief History and an Introduction to the International NGF Meeting Series
Abstract
:1. Pre-Meeting History
2. The First International Meetings
3. The International NGF Meeting Series
Acknowledgments
Author Contributions
Conflicts of Interest
References
- Levi-Montalcini, R. The nerve growth factor 35 years later. Science 1987, 237, 1154–1162. [Google Scholar] [CrossRef] [PubMed]
- Kaplan, D.R.; Miller, F.D. Neurotrophin signal transduction in the nervous system. Curr. Opin. Neurobiol. 2000, 10, 381–391. [Google Scholar] [CrossRef]
- Shooter, E.M. Early days of nerve growth factor proteins. Annu. Rev. Neurosci. 2001, 24, 601–629. [Google Scholar] [CrossRef] [PubMed]
- Thoenen, H.; Sendtner, M. Neurotrophins: From enthusiastic expectations through sobering experiences to rational therapeutic approaches. Nat. Neurosci. 2002, 5, 1046–1050. [Google Scholar] [CrossRef] [PubMed]
- Cohen, S. Origins of growth factors: NGF and EGF. Ann. N. Y. Acad. Sci. 2004, 1038, 98–102. [Google Scholar] [CrossRef] [PubMed]
- Dekkers, M.P.; Nikoletopoulou, V.; Barde, Y.A. Cell biology in neuroscience: Death of developing neurons: New insights and implications for connectivity. J. Cell Biol. 2013, 203, 385–393. [Google Scholar] [CrossRef] [PubMed]
- Hondermarck, H.; Demont, Y.; Bradshaw, R.A. Tropomyosin-Related Kinase Receptor Tyrosine Kinase Family. In Receptor Tyrosine Kinases: Family and Subfamilies; Wheeler, D., Yarden, Y., Eds.; Springer International Publishing: Cham, Switzerland, 2015; pp. 777–820. [Google Scholar]
- Hempstead, B.L. Brain-derived neurotrophic factor: Three ligands, many actions. Trans. Am. Clin. Climatol. Assoc. 2015, 126, 9–19. [Google Scholar] [PubMed]
- Bothwell, M. Recent advances in understanding neurotrophin signaling. F1000Research 2016, 5, 1885. [Google Scholar] [CrossRef] [PubMed]
- Bueker, E.D. Implantation of tumors in the hind limb field of the embryonic chick and the development response of the lumbosacral nervous system. Anat. Rec. 1948, 102, 369–389. [Google Scholar] [CrossRef] [PubMed]
- Cohen, S.; Levi-Montalcini, R.; Hamburger, V. A nerve growth-stimulating factor isolated from sarcomas 37 and 180. Proc. Natl. Acad. Sci. USA 1954, 40, 1014–1018. [Google Scholar] [CrossRef] [PubMed]
- Cohen, S. Purification and metabolic effects of a nerve-growth-promoting protein from Snake Venom. J. Biol. Chem. 1959, 234, 1129–1137. [Google Scholar] [PubMed]
- Cohen, S. Purification of a nerve-growth promoting protein from the mouse salivary gland and its neuro-cytotoxic antiserum. Proc. Natl. Acad. Sci. USA 1960, 46, 302–311. [Google Scholar] [CrossRef] [PubMed]
- Cohen, S. Isolation of a mouse submaxillary gland protein accelerating incisor eruption and eyelid opening in the new-born animal. J. Biol. Chem. 1962, 237, 1555–1562. [Google Scholar] [PubMed]
- Levi-Montalcini, R.; Booker, B. Destruction of the sympathetic ganglia in mammals by an antiserum to a nerve-growth protein. Proc. Natl. Acad. Sci. USA 1960, 46, 384–391. [Google Scholar] [CrossRef] [PubMed]
- Crowley, C.; Spencer, S.D.; Nishimura, M.C.; Chen, K.S.; Pitts-Meek, S.; Armaninil, M.P.; Ling, L.H.; McMahon, S.B.; Shelton, D.L.; Levinson, A.D.; et al. Mice lacking nerve growth factor display perinatal loss of sensory and sympathetic neurons yet develop basal forebrain cholinergic neurons. Cell 1994, 76, 1001–1011. [Google Scholar] [CrossRef]
- Varon, S.; Nomura, J.; Shooter, E.M. The isolation of the mouse nerve growth factor protein in a high molecular weight form. Biochemistry 1967, 6, 2202–2209. [Google Scholar] [CrossRef] [PubMed]
- Smith, A.P.; Varon, S.; Shooter, E.M. Multiple forms of the nerve growth factor protein and its subunits. Biochemistry 1968, 7, 3259–3268. [Google Scholar] [CrossRef] [PubMed]
- Bocchini, V.; Angeletti, P.U. The nerve growth factor: Purification as a 30,000-molecular-weight protein. Proc. Natl. Acad. Sci. USA 1969, 64, 787–794. [Google Scholar] [CrossRef] [PubMed]
- Angeletti, R.H.; Bradshaw, R.A.; Wade, R.D. Subunit structure and amino acid composition of mouse submaxillary gland nerve growth factor. Biochemistry 1971, 10, 463–469. [Google Scholar] [PubMed]
- Angeletti, R.H.; Bradshaw, R.A. Nerve growth factor from mouse submaxillary gland: Amino acid sequence. Proc. Natl. Acad. Sci. USA 1971, 68, 2417–2420. [Google Scholar] [CrossRef] [PubMed]
- Frazier, W.A.; Angeletti, R.H.; Bradshaw, R.A. Nerve growth factor and insulin. Science 1972, 176, 482–488. [Google Scholar] [CrossRef] [PubMed]
- Frazier, W.A.; Boyd, L.F.; Bradshaw, R.A. Interaction of nerve growth factor with surface membranes: Biological competence of insolubilized nerve growth factor. Proc. Natl. Acad. Sci. USA 1973, 70, 2931–2935. [Google Scholar] [CrossRef] [PubMed]
- Banerjee, S.P.; Snyder, S.H.; Cuatrecasas, P.; Greene, L.A. Binding of nerve growth factor receptor in sympathetic ganglia. Proc. Natl. Acad. Sci. USA 1973, 70, 2519–2523. [Google Scholar] [CrossRef] [PubMed]
- Herrup, K.; Shooter, E.M. Properties of the β nerve growth factor receptor of avian dorsal root ganglia. Proc. Natl. Acad. Sci. USA 1973, 70, 3884–3888. [Google Scholar] [CrossRef] [PubMed]
- Frazier, W.A.; Boyd, L.F.; Bradshaw, R.A. Properties of the specific binding of 125I-nerve growth factor to responsive peripheral neurons. J. Biol. Chem. 1974, 249, 5513–5519. [Google Scholar] [PubMed]
- Greene, L.A.; Tischler, A.S. Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc. Natl. Acad. Sci. USA 1976, 73, 2424–2428. [Google Scholar] [CrossRef] [PubMed]
- Hendry, I.A.; Stoeckel, K.; Thoenen, H.; Iversen, L.L. The retrograde axonal transport of nerve growth factor. Brain Res. 1974, 68, 103–121. [Google Scholar] [CrossRef]
- Hendry, I.A.; Stach, R.; Herrup, K. Characteristics of the retrograde axonal transport system for nerve growth factor in the sympathetic nervous system. Brain Res. 1974, 82, 117–128. [Google Scholar] [CrossRef]
- Costrini, N.V.; Bradshaw, R.A. Binding characteristics and apparent molecular size of detergent-solubilized nerve growth factor receptor of sympathetic ganglia. Proc. Natl. Acad. Sci. USA 1979, 76, 3242–3245. [Google Scholar] [CrossRef] [PubMed]
- Massague, J.; Guillette, B.J.; Czech, M.P.; Morgan, C.J.; Bradshaw, R.A. Identification of a nerve growth factor receptor protein in sympathetic ganglia membranes by affinity labeling. J. Biol. Chem. 1981, 256, 9419–9424. [Google Scholar] [PubMed]
- Kouchalakos, R.N.; Bradshaw, R.A. Nerve growth factor receptor from rabbit sympathetic ganglia membranes: Relationship between subforms. J. Biol. Chem. 1986, 261, 16054–16059. [Google Scholar] [PubMed]
- Buxser, S.; Puma, P.; Johnson, G.L. Properties of the nerve growth factor receptor. Relationship between receptor structure and affinity. J. Biol. Chem. 1985, 260, 1917–1926. [Google Scholar] [PubMed]
- Grob, P.M.; Berlot, C.H.; Bothwell, M.A. Affinity labeling and partial purification of nerve growth factor receptors from rat pheochromocytoma and human melanoma cells. Proc. Natl. Acad. Sci. USA 1983, 80, 6819–6823. [Google Scholar] [CrossRef] [PubMed]
- Tait, J.E.; Weinman, S.A.; Bradshaw, R.A. Dissociation kinetics of 125I-nerve growth factor from cell surface receptors: acceleration by unlabeled ligand and its relationship to negative cooperativity. J. Biol. Chem. 1981, 256, 11086–11092. [Google Scholar] [PubMed]
- Radeke, M.J.; Misko, T.P.; Hsu, C.; Herzenberg, L.A.; Shooter, E.M. Gene transfer and molecular cloning of the rat nerve growth factor receptor. Nature 1987, 325, 593–597. [Google Scholar] [CrossRef] [PubMed]
- Johnson, D.; Lanahan, A.; Buck, C.R.; Sehgal, A.; Morgan, C.; Mercer, E.; Bothwell, M.; Chao, M. Expression and structure of the human NGF receptor. Cell 1986, 47, 545–554. [Google Scholar] [CrossRef]
- Scott, J.; Selby, M.; Urdea, M.; Quiroga, M.; Bell, G.I.; Rutter, W.J. Isolation and nucleotide sequence of a cDNA encoding the precursor of mouse nerve growth factor. Nature 1983, 302, 538–540. [Google Scholar] [CrossRef] [PubMed]
- Ullrich, A.; Gray, A.; Cara Berman, C.; Dull, T.J. Human β-nerve growth factor gene sequence highly homologous to that of mouse. Nature 1983, 303, 821–825. [Google Scholar] [CrossRef] [PubMed]
- Frazier, W.A.; Boyd, L.F.; Szutowicz, A.; Pulliam, M.W.; Bradshaw, R.A. Specific binding sites for 125I-nerve growth factor in peripheral tissues and brain. Biochem. Biophys. Res. Comm. 1974, 57, 1096–1103. [Google Scholar] [CrossRef]
- Leibrock, J.; Lottspeich, F.; Hohn, A.; Hofer, M.; Hengerer, B.; Masiakowski, P.; Thoenen, H.; Barde, Y.A. Molecular cloning and expression of brain-derived neurotrophic factor. Nature 1989, 341, 149–152. [Google Scholar] [CrossRef] [PubMed]
- Maisonpierre, P.C.; Belluscio, L.; Squinto, S.; Ip, N.Y.; Furth, M.E.; Lindsay, R.M.; Yancopoulos, G.D. Neurotrophin-3: A neurotrophic factor related to NGF and BDNF. Science 1990, 247, 1446–1451. [Google Scholar] [CrossRef] [PubMed]
- Ip, N.Y.; Ibáñez, C.F.; Nye, S.H.; McClain, J.; Jones, P.F.; Gies, D.R.; Belluscio, L.; Le Beau, M.M.; Espinosa, R.; Squinto, S.P. Mammalian neurotrophin-4: Structure, chromosomal localization, tissue distribution, and receptor specificity. Proc. Natl. Acad. Sci. USA 1992, 89, 3060–3064. [Google Scholar] [CrossRef] [PubMed]
- Rush, R.A. Nerve Growth Factor, Forty Years On. In Proceedings of the International Symposium on Nerve Growth Factor (NGF) and Related Substances, Monterey, CA, USA, 20–23 April 1986; p. 493. [Google Scholar]
- McDonald, N.Q.; Lapatto, R.; Murray-Rust, J.; Gunning, J.; Wlodawer, A.; Blundell, T.L. New protein fold revealed by a 2.3 Å resolution crystal structure of nerve growth factor. Nature 1991, 354, 411–414. [Google Scholar] [CrossRef] [PubMed]
- Olson, L. NGF and the treatment of Alzheimer’s disease. Exp. Neurol. 1993, 124, 5–15. [Google Scholar] [CrossRef] [PubMed]
- Fainzilber, M.; Carter, B. From neurotrophins to immunotrophins. NGF2002: The seventh international conference on NGF and related molecules. EMBO Rep. 2002, 3, 1029–1034. [Google Scholar] [CrossRef] [PubMed]
- Plotkin, J.L.; Wu, C. Neurotrophin biology at NGF 2016: From fundamental science to clinical applications. Int. J. Dev. Neurosci. 2017, 56, 27–34. [Google Scholar] [CrossRef] [PubMed]
Location | Monterey | Daydream Island | Lake Louise | Herstmonceux | Stockholm | Montreal | Modena | Lyon | Upper Galilee | Helsinki | Wurzburg | Suzhou | Monterey |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Topic/Year | 1986 | 1991 | 1994 | 1996 | 1998 | 2000 | 2002 | 2006 | 2008 | 2010 | 2012 | 2014 | 2016 |
Biosynthesis/Chemistry | |||||||||||||
Receptor Identification | |||||||||||||
Signalling | |||||||||||||
Development/Differentiation | |||||||||||||
NTs in CNS | |||||||||||||
Other Factors | |||||||||||||
Connectivity | |||||||||||||
Injury/Repair | |||||||||||||
Therapeutics/Clinical Trials | |||||||||||||
Regulation of Synthesis | |||||||||||||
Non-Neuronal Functions | |||||||||||||
Pain | |||||||||||||
Stem Cells | |||||||||||||
Memory/Behaviour | |||||||||||||
Synaptic Function/Circuitry/Plasticity | |||||||||||||
Pro Neurotrophins |
© 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Share and Cite
Bradshaw, R.A.; Mobley, W.; Rush, R.A. Nerve Growth Factor and Related Substances: A Brief History and an Introduction to the International NGF Meeting Series. Int. J. Mol. Sci. 2017, 18, 1143. https://doi.org/10.3390/ijms18061143
Bradshaw RA, Mobley W, Rush RA. Nerve Growth Factor and Related Substances: A Brief History and an Introduction to the International NGF Meeting Series. International Journal of Molecular Sciences. 2017; 18(6):1143. https://doi.org/10.3390/ijms18061143
Chicago/Turabian StyleBradshaw, Ralph A., William Mobley, and Robert A. Rush. 2017. "Nerve Growth Factor and Related Substances: A Brief History and an Introduction to the International NGF Meeting Series" International Journal of Molecular Sciences 18, no. 6: 1143. https://doi.org/10.3390/ijms18061143