Next Article in Journal
Talin Modulation by a Synthetic N-Acylurea Derivative Reduces Angiogenesis in Human Endothelial Cells
Next Article in Special Issue
An Integrated View of Aristolochic Acid Nephropathy: Update of the Literature
Previous Article in Journal
Therapeutic Potential of Induced Neural Stem Cells for Parkinson’s Disease
Previous Article in Special Issue
Influence of Tyrosine Kinase Inhibitors on Hypertension and Nephrotoxicity in Metastatic Renal Cell Cancer Patients
 
 
Review

What Do We Know about Opioids and the Kidney?

Department of Internal Medicine, State University of New York at Downstate, Brooklyn, New York, NY 11203, USA
*
Author to whom correspondence should be addressed.
Academic Editor: Monica Valentovic
Int. J. Mol. Sci. 2017, 18(1), 223; https://doi.org/10.3390/ijms18010223
Received: 21 November 2016 / Revised: 30 December 2016 / Accepted: 17 January 2017 / Published: 22 January 2017
(This article belongs to the Special Issue Nephrotoxicity)
Evidence suggests a link between opioid use and kidney disease. This review summarizes the known renal manifestations of opioid use including its role in acute and chronic kidney injury. Both the direct and indirect effects of the drug, and the context which leads to the development of renal failure, are explored. While commonly used safely for pain control and anesthesia in those with kidney disease, the concerns with respect to side effects and toxicity of opioids are addressed. This is especially relevant with the worldwide increase in the use of opioids for medical and recreational use. View Full-Text
Keywords: opioids; renal failure; pharmacokinetics opioids; renal failure; pharmacokinetics
Show Figures

Figure 1

MDPI and ACS Style

Mallappallil, M.; Sabu, J.; Friedman, E.A.; Salifu, M. What Do We Know about Opioids and the Kidney? Int. J. Mol. Sci. 2017, 18, 223. https://doi.org/10.3390/ijms18010223

AMA Style

Mallappallil M, Sabu J, Friedman EA, Salifu M. What Do We Know about Opioids and the Kidney? International Journal of Molecular Sciences. 2017; 18(1):223. https://doi.org/10.3390/ijms18010223

Chicago/Turabian Style

Mallappallil, Mary, Jacob Sabu, Eli A. Friedman, and Moro Salifu. 2017. "What Do We Know about Opioids and the Kidney?" International Journal of Molecular Sciences 18, no. 1: 223. https://doi.org/10.3390/ijms18010223

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop