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Int. J. Mol. Sci. 2016, 17(3), 425;

Nocturnal Pruritus: The Battle for a Peaceful Night’s Sleep

Department of Dermatology/Temple Itch Center, Lewis Katz School of Medicine, Temple University, 3322 North Broad Street-Suite 212, Philadelphia, PA 19140, USA
Department of Neurosciences, Royal Victoria Hospital, 274 Grosvenor Road, Belfast, Northern Ireland BT12 6BA, UK
Author to whom correspondence should be addressed.
Academic Editor: Elma Baron
Received: 8 March 2016 / Revised: 16 March 2016 / Accepted: 16 March 2016 / Published: 22 March 2016
(This article belongs to the Special Issue Sleep, Circadian Rhythm and Skin)
Full-Text   |   PDF [568 KB, uploaded 22 March 2016]   |  


Chronic pruritus is a debilitating condition with numerous etiologies. Many patients suffer from nocturnal pruritus, which can decrease quality of life and affect mortality in hemodialysis patients. Nocturnal pruritus may occur in all sleep stages but is most prevalent in stages N1 and N2. Further research is needed to elucidate the pathophysiology of nocturnal itch, which will aid in the development of tailored management strategies. View Full-Text
Keywords: sleep; pruritus; physiology; sleep cycle; circadian rhythm; atopic dermatitis sleep; pruritus; physiology; sleep cycle; circadian rhythm; atopic dermatitis

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Lavery, M.J.; Stull, C.; Kinney, M.O.; Yosipovitch, G. Nocturnal Pruritus: The Battle for a Peaceful Night’s Sleep. Int. J. Mol. Sci. 2016, 17, 425.

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Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
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