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Metabolomics, a Powerful Tool for Agricultural Research
Review

Nutrimetabolomics: An Update on Analytical Approaches to Investigate the Role of Plant-Based Foods and Their Bioactive Compounds in Non-Communicable Chronic Diseases

1
Department of Biochemistry and Molecular Biology II, Institute of Nutrition and Food Technology “José Mataix”, Center for Biomedical Research, University of Granada, 18100 Granada, Spain
2
Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición, Ciberobn, 28029 Madrid, Spain
*
Author to whom correspondence should be addressed.
Academic Editors: Vito Verardo and David Arráez-Román
Int. J. Mol. Sci. 2016, 17(12), 2072; https://doi.org/10.3390/ijms17122072
Received: 24 October 2016 / Revised: 28 November 2016 / Accepted: 3 December 2016 / Published: 9 December 2016
(This article belongs to the Special Issue Lipidomics and Glycomics: New Advances in Food Science and Nutrition)
Metabolomics is the study of low-weight molecules present in biological samples such as biofluids, tissue/cellular extracts, and culture media. Metabolomics research is increasing, and at the moment, it has several applications in the food science and nutrition fields. In the present review, we provide an update about the most frequently used methodologies and metabolomic platforms in these areas. Also, we discuss different metabolomic strategies regarding the discovery of new bioactive compounds (BACs) in plant-based foods. Furthermore, we review the existing literature related to the use of metabolomics to investigate the potential protective role of BACs in the prevention and treatment of non-communicable chronic diseases, namely cardiovascular disease, diabetes, and cancer. View Full-Text
Keywords: bioactive compounds; metabolomics; non-communicable chronic diseases; nutrimetabolomics; plant-based food bioactive compounds; metabolomics; non-communicable chronic diseases; nutrimetabolomics; plant-based food
MDPI and ACS Style

Rangel-Huerta, O.D.; Gil, A. Nutrimetabolomics: An Update on Analytical Approaches to Investigate the Role of Plant-Based Foods and Their Bioactive Compounds in Non-Communicable Chronic Diseases. Int. J. Mol. Sci. 2016, 17, 2072. https://doi.org/10.3390/ijms17122072

AMA Style

Rangel-Huerta OD, Gil A. Nutrimetabolomics: An Update on Analytical Approaches to Investigate the Role of Plant-Based Foods and Their Bioactive Compounds in Non-Communicable Chronic Diseases. International Journal of Molecular Sciences. 2016; 17(12):2072. https://doi.org/10.3390/ijms17122072

Chicago/Turabian Style

Rangel-Huerta, Oscar D., and Angel Gil. 2016. "Nutrimetabolomics: An Update on Analytical Approaches to Investigate the Role of Plant-Based Foods and Their Bioactive Compounds in Non-Communicable Chronic Diseases" International Journal of Molecular Sciences 17, no. 12: 2072. https://doi.org/10.3390/ijms17122072

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Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

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