Research Advances on Pathways of Nickel-Induced Apoptosis
AbstractHigh concentrations of nickel (Ni) are harmful to humans and animals. Ni targets a number of organs and produces multiple toxic effects. Apoptosis is important in Ni-induced toxicity of the kidneys, liver, nerves, and immune system. Apoptotic pathways mediated by reactive oxygen species (ROS), mitochondria, endoplasmic reticulum (ER), Fas, and c-Myc participate in Ni-induced cell apoptosis. However, the exact mechanism of apoptosis caused by Ni is still unclear. Understanding the mechanism of Ni-induced apoptosis may help in designing measures to prevent Ni toxicity. View Full-Text
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Guo, H.; Chen, L.; Cui, H.; Peng, X.; Fang, J.; Zuo, Z.; Deng, J.; Wang, X.; Wu, B. Research Advances on Pathways of Nickel-Induced Apoptosis. Int. J. Mol. Sci. 2016, 17, 10.
Guo H, Chen L, Cui H, Peng X, Fang J, Zuo Z, Deng J, Wang X, Wu B. Research Advances on Pathways of Nickel-Induced Apoptosis. International Journal of Molecular Sciences. 2016; 17(1):10.Chicago/Turabian Style
Guo, Hongrui; Chen, Lian; Cui, Hengmin; Peng, Xi; Fang, Jing; Zuo, Zhicai; Deng, Junliang; Wang, Xun; Wu, Bangyuan. 2016. "Research Advances on Pathways of Nickel-Induced Apoptosis." Int. J. Mol. Sci. 17, no. 1: 10.
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