The kin17 Protein in Murine Melanoma Cells
Abstractkin17 has been described as a protein involved in the processes of DNA replication initiation, DNA recombination, and DNA repair. kin17 has been studied as a potential molecular marker of breast cancer. This work reports the detection and localization of this protein in the murine melanoma cell line B16F10-Nex2 and in two derived subclones with different metastatic potential, B16-8HR and B16-10CR. Nuclear and chromatin-associated protein fractions were analyzed, and kin17 was detected in all fractions, with an elevated concentration observed in the chromatin-associated fraction of the clone with low metastatic potential, suggesting that the kin17 expression level could be a marker of melanoma. View Full-Text
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Ramos, A.C.; Gaspar, V.P.; Kelmer, S.M.G.; Sellani, T.A.; Batista, A.G.U.; De Lima Neto, Q.A.; Rodrigues, E.G.; Fernandez, M.A. The kin17 Protein in Murine Melanoma Cells. Int. J. Mol. Sci. 2015, 16, 27912-27920.
Ramos AC, Gaspar VP, Kelmer SMG, Sellani TA, Batista AGU, De Lima Neto QA, Rodrigues EG, Fernandez MA. The kin17 Protein in Murine Melanoma Cells. International Journal of Molecular Sciences. 2015; 16(11):27912-27920.Chicago/Turabian Style
Ramos, Anelise C.; Gaspar, Vanessa P.; Kelmer, Sabrina M.G.; Sellani, Tarciso A.; Batista, Ana G.U.; De Lima Neto, Quirino A.; Rodrigues, Elaine G.; Fernandez, Maria A. 2015. "The kin17 Protein in Murine Melanoma Cells." Int. J. Mol. Sci. 16, no. 11: 27912-27920.