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Int. J. Mol. Sci. 2013, 14(11), 22011-22021;

Modeling Human Liver Biology Using Stem Cell-Derived Hepatocytes

Shantou University Medical College, Shantou 515041, China
MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh EH16 4UU, UK
MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow G11 5JR, UK
Author to whom correspondence should be addressed.
Received: 28 September 2013 / Revised: 28 October 2013 / Accepted: 30 October 2013 / Published: 6 November 2013
(This article belongs to the Special Issue Xenobiotic Metabolism)
Full-Text   |   PDF [396 KB, uploaded 19 June 2014]


Stem cell-derived hepatocytes represent promising models to study human liver biology and disease. This concise review discusses the recent progresses in the field, with a focus on human liver disease, drug metabolism and virus infection. View Full-Text
Keywords: drug metabolism; liver disease; stem cell; stem cell-derived hepatocytes; cell based models drug metabolism; liver disease; stem cell; stem cell-derived hepatocytes; cell based models
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Sun, P.; Zhou, X.; Farnworth, S.L.; Patel, A.H.; Hay, D.C. Modeling Human Liver Biology Using Stem Cell-Derived Hepatocytes. Int. J. Mol. Sci. 2013, 14, 22011-22021.

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