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Open AccessCase Report

Successful Treatment of Liver Aspergilloma by Caspofungin Acetate First-Line Therapy in a Non-Immunocompromised Patient

1
Department of Hematology, State Allogeneic Hematopoietic Stem Cell Transplantation Center, Xijing Hospital, Fourth Military Medical University, Xi’an 710032, China
2
Department of Radiology and Medical Imaging Center, Xijing Hospital, Fourth Military Medical University, Xi’an 710032, China
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2012, 13(9), 11063-11070; https://doi.org/10.3390/ijms130911063
Received: 18 July 2012 / Revised: 20 August 2012 / Accepted: 29 August 2012 / Published: 6 September 2012
(This article belongs to the Special Issue Molecular Self-Assembly 2012)
Aspergillosis remains to be a life-threatening complication in immunocompromised patients. However, Aspergillus infection can be observed in non-immunocompromised individuals in rare cases. We report a case of liver aspergilloma in a chronic aplastic anemia patient under relatively intact immune status. Therapeutic strategy for this rare condition was extensively discussed and caspofungin acetate single agent first-line therapy was applied after careful consideration. Encouraging clinical and radiologic improvements were achieved in response to the antifungal salvage. Our long-term follow-up study also revealed a favorable prognosis. Based on this experience, we suggest caspofungin acetate as first-line therapy for treatment plans of liver aspergilloma. View Full-Text
Keywords: aspergillosis; liver; Aspergillus fumigatus; caspofungin acetate aspergillosis; liver; Aspergillus fumigatus; caspofungin acetate
MDPI and ACS Style

Bai, Q.-X.; Huan, Y.; Wang, J.-H.; Yang, L.-J.; Dong, H.-J. Successful Treatment of Liver Aspergilloma by Caspofungin Acetate First-Line Therapy in a Non-Immunocompromised Patient. Int. J. Mol. Sci. 2012, 13, 11063-11070.

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