Next Article in Journal
Time-Resolved Soft X-ray Diffraction Reveals Transient Structural Distortions of Ternary Liquid Crystals
Previous Article in Journal
The Cladistic Basis for the Phylogenetic Diversity (PD) Measure Links Evolutionary Features to Environmental Gradients and Supports Broad Applications of Microbial Ecology’s “Phylogenetic Beta Diversity” Framework
 
Search for Articles:
Title / Keyword
Author / Affiliation
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
Journals
IJMS
Volume 10
Issue 11
10.3390/ijms10114742
ijms-logo
Submit to this Journal Review for this Journal Edit a Special Issue
► Article Menu

Article Menu

share announcement thumb_up
...
textsms
...
Open AccessArticle

Antinociceptive and Anti-Inflammatory Effects of Ethanolic Extracts of Glycine max (L.) Merr and Rhynchosia nulubilis Seeds

by
Joo Hyuk Yim
1,
Ok-Hwan Lee
2,*,
Ung-Kyu Choi
3 and
Young-Chan Kim
1,*
1
Korea Food Research Institute, Seongnam, Kyonggi, 463-746, Korea
2
Department of Biomedical Science, CHA University, Seongnam, Kyonggi, 463-836, Korea
3
Pohang Center for Evaluation of Biomaterials, Pohang 790-834, Korea
*
Authors to whom correspondence should be addressed.
Int. J. Mol. Sci. 2009, 10(11), 4742-4753; https://doi.org/10.3390/ijms10114742
Received: 11 October 2009 / Revised: 2 November 2009 / Accepted: 4 November 2009 / Published: 4 November 2009
(This article belongs to the Section Biochemistry)
View Full-Text Download PDF

Abstract

The aim of this study was to assess the in vivo potential of ethanolic extracts of Glycine max (L.) Merr. (SoRiTae) and Rhynchosia nulubilis (Yak-Kong) seeds as natural anti-nociceptive and anti-inflammatory agents. To assess the anti-nociceptive and antiinflammatory potential, the ethanolic extracts of SoRiTae and Yak-Kong seeds were tested in arachidonic acid-induced ear edema, carrageenan induced paw edema, formalin-induced licking time, acetic acid induced writhing and hot plate-induced thermal stimulation in mice. The administration of ethanolic extracts of SoRiTae and Yak-Kong seeds evoked a significant effect of anti-nociceptive and anti-inflammatory activities as compared to standards aminopyrine and indomethacin. The ear edema, paw edema, paw licking time, pain and writhes in mice were significantly reduced (p < 0.05) as compared to the control. The results obtained in this study indicate that both SoRiTae and Yak-Kong soybeans possesses potential anti-nociceptive and anti-inflammatory activities. View Full-Text
Keywords: Glycine max; Rhynchosia nulubilis; anti-inflammatory activity; anti-nociceptive activity Glycine max; Rhynchosia nulubilis; anti-inflammatory activity; anti-nociceptive activity
This is an open access article distributed under the Creative Commons Attribution License
SciFeed

Share and Cite

MDPI and ACS Style

Yim, J.H.; Lee, O.-H.; Choi, U.-K.; Kim, Y.-C. Antinociceptive and Anti-Inflammatory Effects of Ethanolic Extracts of Glycine max (L.) Merr and Rhynchosia nulubilis Seeds. Int. J. Mol. Sci. 2009, 10, 4742-4753. https://doi.org/10.3390/ijms10114742

AMA Style

Yim JH, Lee O-H, Choi U-K, Kim Y-C. Antinociceptive and Anti-Inflammatory Effects of Ethanolic Extracts of Glycine max (L.) Merr and Rhynchosia nulubilis Seeds. International Journal of Molecular Sciences. 2009; 10(11):4742-4753. https://doi.org/10.3390/ijms10114742

Chicago/Turabian Style

Yim, Joo Hyuk; Lee, Ok-Hwan; Choi, Ung-Kyu; Kim, Young-Chan. 2009. "Antinociceptive and Anti-Inflammatory Effects of Ethanolic Extracts of Glycine max (L.) Merr and Rhynchosia nulubilis Seeds" Int. J. Mol. Sci. 10, no. 11: 4742-4753. https://doi.org/10.3390/ijms10114742

Find Other Styles

Article Metrics

Article Access Map by Country/Region

1
Only visits after 24 November 2015 are recorded.
Search more from Scilit
 
Search
Back to TopTop