Next Article in Journal
Recent Advances in Development of Small Molecules to Fight Cancer—Second Edition
Previous Article in Journal
Quantitative Analysis of Bisphenol A in Commercial Beverages
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Molecules
Volume 31
Issue 5
10.3390/molecules31050806
molecules-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
Correction to Molecules 2020, 25(1), 15.
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Correction

Correction: Zhang et al. Protopine Protects Mice Against LPS-Induced Acute Kidney Injury by Inhibiting Apoptosis and Inflammation via the TLR4 Signaling Pathway. Molecules 2020, 25, 15

by
Beibei Zhang
1,2,
Mengnan Zeng
1,2,
Meng Li
1,2,
Yuxuan Kan
1,2,
Benke Li
1,2,
Ruiqi Xu
1,2,
Yuanyuan Wu
1,2,
Shengchao Wang
1,2,
Xiaoke Zheng
1,2,* and
Weisheng Feng
1,2,*
1
College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, China
2
Collaborative Innovation Center for Respiratory Disease Diagnosis and Treatment & Chinese Medicine Development of Henan Province, Zhengzhou 450046, China
*
Authors to whom correspondence should be addressed.
Molecules 2026, 31(5), 806; https://doi.org/10.3390/molecules31050806
Submission received: 29 July 2025 / Revised: 8 November 2025 / Accepted: 12 February 2026 / Published: 28 February 2026
Browse Figures
Versions Notes

Error in Figure

In the original publication [1], there was a mistake in Figure 4G and Figure 5 as published. The bonds of IL1β in Figure 4 were copied by mistake, and the corrected Figure 4 appears below. In addition, Figure 5C was also copied by mistake, and the corrected Figure 5 appears below. The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.

Reference

  1. Zhang, B.; Zeng, M.; Li, M.; Kan, Y.; Li, B.; Xu, R.; Wu, Y.; Wang, S.; Zheng, X.; Feng, W. Protopine Protects Mice against LPS-Induced Acute Kidney Injury by Inhibiting Apoptosis and Inflammation via the TLR4 Signaling Pathway. Molecules 2020, 25, 15. [Google Scholar] [CrossRef] [Scilit] [PubMed]
Molecules 31 00806 g004
Figure 4. Effects of protopine on inflammatory response in mice with LPS-induced AKI (n = 8 mice per group). (A) Effects of protopine on inflammation accumulation in mice with LPS-induced AKI detected by small animal imaging. (B–E) Effects of protopine on inflammatory cytokines in mice with LPS-induced AKI. (F,G) Effects of protopine on TLR4 signaling pathway in mice with LPS-induced AKI. (F1) TLR4. (F2) Myd88. (F3) p-p65/p65. (G1) NLRP3. (G2) Caspase1/pro Caspase1. (G3) IL-1β. (G4) IL1R1. (G5) GSDMD. * p < 0.05, ** p < 0.01 compared with the LPS group. (LPRO: low-dose protopine; MPRO: medium-dose protopine; HPRO: high-dose protopine; LPS: lipopolysaccharide; AKI: acute kidney injury; TLR4: toll-like receptor 4; NLRP3: nod receptor heat protein domain associated protein 3; IL-1β: interleukin-1β; IL1R1: interleukin-1 receptor 1; GSDMD: gasdermin; MyD88: myeloid differentiation factor88).
Figure 4. Effects of protopine on inflammatory response in mice with LPS-induced AKI (n = 8 mice per group). (A) Effects of protopine on inflammation accumulation in mice with LPS-induced AKI detected by small animal imaging. (B–E) Effects of protopine on inflammatory cytokines in mice with LPS-induced AKI. (F,G) Effects of protopine on TLR4 signaling pathway in mice with LPS-induced AKI. (F1) TLR4. (F2) Myd88. (F3) p-p65/p65. (G1) NLRP3. (G2) Caspase1/pro Caspase1. (G3) IL-1β. (G4) IL1R1. (G5) GSDMD. * p < 0.05, ** p < 0.01 compared with the LPS group. (LPRO: low-dose protopine; MPRO: medium-dose protopine; HPRO: high-dose protopine; LPS: lipopolysaccharide; AKI: acute kidney injury; TLR4: toll-like receptor 4; NLRP3: nod receptor heat protein domain associated protein 3; IL-1β: interleukin-1β; IL1R1: interleukin-1 receptor 1; GSDMD: gasdermin; MyD88: myeloid differentiation factor88).
Molecules 31 00806 g004
Molecules 31 00806 g005
Figure 5. Effects of protopine on the blood cell subtype in mice with. LPS-induced AKI (n = 8 mice per group). (A) Gating Strategy. (B) Effects of protopine on the blood cell subtype ratio in mice with LPS-induced AKI. (C,D) Effects of protopine on the ratio of CD45+Ly-6G+ and CD45+F4/80+ in mice with LPS-induced AKI. ** p < 0.01 compared with the LPS group. (LPRO: low-dose protopine; MPRO: medium-dose protopine; HPRO: high-dose protopine; LPS: lipopolysaccharide; AKI: acute kidney injury).
Figure 5. Effects of protopine on the blood cell subtype in mice with. LPS-induced AKI (n = 8 mice per group). (A) Gating Strategy. (B) Effects of protopine on the blood cell subtype ratio in mice with LPS-induced AKI. (C,D) Effects of protopine on the ratio of CD45+Ly-6G+ and CD45+F4/80+ in mice with LPS-induced AKI. ** p < 0.01 compared with the LPS group. (LPRO: low-dose protopine; MPRO: medium-dose protopine; HPRO: high-dose protopine; LPS: lipopolysaccharide; AKI: acute kidney injury).
Molecules 31 00806 g005
Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content.

Share and Cite

MDPI and ACS Style

Zhang, B.; Zeng, M.; Li, M.; Kan, Y.; Li, B.; Xu, R.; Wu, Y.; Wang, S.; Zheng, X.; Feng, W. Correction: Zhang et al. Protopine Protects Mice Against LPS-Induced Acute Kidney Injury by Inhibiting Apoptosis and Inflammation via the TLR4 Signaling Pathway. Molecules 2020, 25, 15. Molecules 2026, 31, 806. https://doi.org/10.3390/molecules31050806

AMA Style

Zhang B, Zeng M, Li M, Kan Y, Li B, Xu R, Wu Y, Wang S, Zheng X, Feng W. Correction: Zhang et al. Protopine Protects Mice Against LPS-Induced Acute Kidney Injury by Inhibiting Apoptosis and Inflammation via the TLR4 Signaling Pathway. Molecules 2020, 25, 15. Molecules. 2026; 31(5):806. https://doi.org/10.3390/molecules31050806

Chicago/Turabian Style

Zhang, Beibei, Mengnan Zeng, Meng Li, Yuxuan Kan, Benke Li, Ruiqi Xu, Yuanyuan Wu, Shengchao Wang, Xiaoke Zheng, and Weisheng Feng. 2026. "Correction: Zhang et al. Protopine Protects Mice Against LPS-Induced Acute Kidney Injury by Inhibiting Apoptosis and Inflammation via the TLR4 Signaling Pathway. Molecules 2020, 25, 15" Molecules 31, no. 5: 806. https://doi.org/10.3390/molecules31050806

APA Style

Zhang, B., Zeng, M., Li, M., Kan, Y., Li, B., Xu, R., Wu, Y., Wang, S., Zheng, X., & Feng, W. (2026). Correction: Zhang et al. Protopine Protects Mice Against LPS-Induced Acute Kidney Injury by Inhibiting Apoptosis and Inflammation via the TLR4 Signaling Pathway. Molecules 2020, 25, 15. Molecules, 31(5), 806. https://doi.org/10.3390/molecules31050806

Article Metrics

Back to TopTop